Results 91 to 100 of about 3,955,879 (295)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Two Types of Solutions to a Class of (p,q)-Laplacian Systems with Critical Sobolev Exponents in RN
Advances in Mathematical Physics, 2018 We focus on the following elliptic system with critical Sobolev exponents: -div∇up-2∇u+m(x)up-2u=λup⁎-2u+(1/η)Gu(u,v), x∈RN; -div∇vq-2∇v+n(x)vq-2v=μvq⁎-2v+(1/η)Gv(u,v), x∈RN; u(x)>0,v(x)>0, x∈RN, where μ,λ>0 ...
Jing Li, Caisheng Chen
doaj +1 more source
Noncritical String Field Theory for 2d Quantum Gravity Coupled to (p, q)-Conformal Fields [PDF]
International Journal of Modern Physics A, 1997 We propose a noncritical string field theory for 2d quantum gravity coupled to (p, q) conformal fields. The Hamiltonian is described by the generators of the Wp algebra, and the Schwinger–Dyson equation is equivalent to a vacuum condition imposed on the generators of Wp algebra.
Ambjørn, Jan, Watabiki, Y.
openaire +3 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Abstract and Applied Analysis, 2013 The matrix equation ∑l=1uAlXBl+∑s=1vCsXTDs=F, which includes some frequently investigated matrix equations as its special cases, plays important roles in the system theory.
Ning Li, Qing-Wen Wang
doaj +1 more source
About the Dedekind psi function in Pauli graphs [PDF]
, 2010 We study the commutation structure within the Pauli groups built on all decompositions of a given Hilbert space dimension $q$, containing a square, into its factors.
Planat, Michel R. P.
core +2 more sources
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Non-relativistic limit of the Mielke–Baekler gravity theory
European Physical Journal C: Particles and FieldsIn this paper, we present a generalized non-relativistic Chern–Simons gravity model in three spacetime dimensions. We first study the non-relativistic limit of the Mielke–Baekler gravity through a contraction process.
Patrick Concha +2 more
doaj +1 more source
Two Loop Renormalization of Massive (p,q) Supersymmetric Sigma Models
, 1995 We calculate the beta-functions of the general massive (p,q) supersymmetric sigma model to two loop order using (1,0) superfields. The conditions for finiteness are discussed in relation to (p,q) supersymmetry.
Allen +39 more
core +2 more sources