Results 81 to 90 of about 24,158,011 (265)
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Soluble P-selectin is the smoke, not the fire [PDF]
Blood, 2017 In this issue of Blood , Panicker and colleagues have clarified the role of soluble P-selectin (sP-selectin) in inflammation and cardiovascular disease by showing that monomeric sP-selectin, the form that circulates in plasma, does not promote inflammation or promote coagulation, but the dimeric form of P-selectin does ...
openaire +2 more sources
P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin. [PDF]
The Journal of cell biology, 1995 Neutrophils roll on P-selectin expressed by activated platelets or endothelial cells under the shear stresses in the microcirculation. P-selectin glycoprotein ligand-1 (PSGL-1) is a high affinity ligand for P-selectin on myeloid cells. However, it has not been demonstrated that PSGL-1 contributes to the rolling of neutrophils on P-selectin.
K L, Moore +8 more
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Arthritis &Rheumatology, EarlyView.Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
Journal of Pharmacological Sciences, 2007 Angiotensin II (AII) has been reported to induce leukocyte adhesion to endothelium through up-regulation of P-selectin surface expression. However, the underlying molecular and cellular mechanisms remain unknown.
Xiaona Ge, Brad Low, Mei Liang, Jian Fu
doaj +1 more source
P-selectin-mediated platelet adhesion promotes the metastasis of murine melanoma cells. [PDF]
PLoS ONE, 2014 Studies have indicated that the aggregation of activated platelets with cancer cells facilitates tumor metastasis; the adhesion molecule P-selectin may be an important mediator of this process, but the detailed mechanism is unclear. In the current study,
Cui-Ling Qi +9 more
doaj +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Evaluation the value of markers for prediction of portal vein thrombosis after devascularization
Annals of Hepatology, 2015 Aim. To evaluate the value of D-dimer and P-selectin in cirrhotic portal hypertension (PHT) patients for prediction of portal vein thrombosis (PVT) after devascularization.Material and methods.
Yang Fei +2 more
doaj +1 more source
Thrombosis Journal, 2021 Background Myeloid cells express microparticles that could increase the expression of adhesion molecules including P-selectin. We aimed to evaluate the level of soluble P-selectin (sP-selectin) and prothrombin fragment 1 + 2 (F1 + 2), and to determine ...
Lugyanti Sukrisman
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