Results 81 to 90 of about 53,857 (243)

Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions

open access: yesHaematologica, 2007
Background and Objectives P-selectin has been implicated in important platelet functions. However, neither its role in thrombus formation and cardiovascular disorders nor its suitability as a therapeutic target structure is entirely clear.Design and ...
Gertie J. Oostingh   +6 more
doaj   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

Differences of Main Levels of Serum P-Selectin and Trombosite in Severe Preeclampsia and Eclampsia

open access: yesAndalas Obstetrics and Gynecology Journal, 2017
Preeclampsia-eclampsia is a main complication of pregnancy in which the incidence is increasing world-wide and is associated with maternal morbidity and mortality.
Joserizal Serudji   +2 more
doaj   +1 more source

P-selectin

open access: yes
Citation: 'P-selectin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13531 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Baseline Neutrophil‐To‐Lymphocyte Ratio as a Risk Stratification Marker for Severe Checkpoint Inhibitor Pneumonitis in Patients With Non‐Small Cell Lung Cancer: A Two‐Cohort Study With Retrospective Discovery and Prospective Validation

open access: yesRespirology, EarlyView.
The association between baseline neutrophil‐to‐lymphocyte ratio (NLR) and severe checkpoint inhibitor pneumonitis (CIP) was analyzed in discovery retrospective and validation prospective cohorts. Higher baseline NLR (≥ 4.75) was associated with increased severe CIP incidence in both cohorts.
Tetsu Hirakawa   +24 more
wiley   +1 more source

Serum Profiling of Proinflammatory Mediators in Inflammatory Bowel Disease: Indication for Use in Differential Diagnosis

open access: yesApplied Sciences
Inflammatory Bowel Disease (IBD) is a group of chronic intestinal diseases, among which Crohn’s disease (CD) and ulcerative colitis (UC) represent the two main types.
Aleksandra Górecka   +5 more
doaj   +1 more source

The Role of Interfacial Energetics and Defects on The Efficiency of Tin Perovskite Solar Cells

open access: yesSmall, EarlyView.
ABSTRACT Tin perovskites are emerging as a sustainable alternative to lead‐based photovoltaics, yet their efficiency remains limited by energy‐level mismatch and intrinsic instability from tin oxidation. Progress is further hindered by inconsistent electrical behavior, obscuring the true bottlenecks of device performance.
Mahmoud H. Aldamasy   +15 more
wiley   +1 more source

P-selectin levels in women with endometriosis and non-endometriosis

open access: yesQanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2017
The discovery of a decline in the cellular immune system in endometrial tissue of women with endometriosis triggers the idea that immunologic factors may play a role in the process of endometriosis.
Tonny Simarmata
doaj  

Association of Peripheral Monocyte Count with Soluble P-Selectin and Advanced Stages in Nasopharyngeal Carcinoma

open access: yesAdvances in Hematology, 2018
Introduction. Inflammation is widely recognized to play an important role in cancer progression and is related to thrombosis. Soluble P-selectin (sP-selectin) is one of several biomarkers that may be predictive of thrombosis in cancer.
Adi Surya Komala, Andhika Rachman
doaj   +1 more source

Enhancement of immune checkpoint inhibitor efficacy by DHX58+ SELL+ T cells in advanced gastric cancer

open access: yesVIEW, EarlyView.
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen   +9 more
wiley   +1 more source

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