Interaction of p-synephrine on the pharmacodynamics and pharmacokinetics of gliclazide in animal models [PDF]
Journal of Ayurveda and Integrative Medicine, 2018 Background: Type 2 diabetes is frequently seen in patients suffering from obesity. p-synephrine and gliclazide are widely used medicines for the treatment of obesity and diabetes, respectively.
Leela Krishna Vatsavai +1 more
doaj +5 more sources
Combined Anti-Adipogenic Effects of Hispidulin and p-Synephrine on 3T3-L1 Adipocytes [PDF]
Biomolecules, 2021 Hispidulin is abundant in Arrabidaea chica, Crossostephium chinense, and Grindelia argentina, among others. p-Synephrine is the main phytochemical constituent of Citrus aurantium.
Dahae Lee +5 more
doaj +6 more sources
p-Synephrine: an overview of physicochemical properties, toxicity, biological and pharmacological activity [PDF]
EXCLI Journal : Experimental and Clinical Sciencesp-Synephrine is a popular ingredient in dietary supplements. It is also found in trace amounts in living organisms. It is advertised as a weight loss supplement and it is supposed to improve performance in sports.
Maciej Kulawik +2 more
doaj +6 more sources
Effects of <em>Citrus aurantium</em> (Bitter Orange) Fruit Extracts and <em>p</em>-Synephrine on Metabolic Fluxes in the Rat Liver [PDF]
Molecules, 2012 The fruit extracts<strong> </strong>of<strong> </strong><em>Citrus aurantium</em> (bitter orange) are traditionally used as weight-loss products and as appetite supressants.
Rosane Marina Peralta +6 more
doaj +6 more sources
A Review of the Human Clinical Studies Involving Citrus aurantium (Bitter Orange) Extract and its Primary Protoalkaloid p-Synephrine [PDF]
International Journal of Medical Sciences, 2012 This review summarizes the published as well as unpublished human studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine, providing information and an assessment of the safety and efficacy of these widely ...
Sidney J. Stohs, Harry G. Preuss, Mohd Shara
doaj +4 more sources
Synephrine potentiates lidocaine‐induced cutaneous analgesia via α‐adrenergic receptors in male rats [PDF]
Physiological ReportsThis study aimed to assess the cutaneous analgesic effect of the lidocaine–synephrine combination and its underlying α‐adrenergic receptor‐mediated mechanism in comparison with phenylephrine.
An‐Kuo Chou +5 more
doaj +3 more sources
p-Synephrine Indicates Internal Maturity of Citrus grandis (L.) Osbeck cv. Mato Peiyu—Reclaiming Functional Constituents from Nonedible Parts [PDF]
Molecules, 2023 The processing of Citrus grandis Osbeck cv. Mato Peiyu (CGMP) fruits generates a considerable amount of waste, mainly the flavedo, albedo, and segment membrane; the generated waste yields severe environmental and economic challenges.
Li-Yun Lin +4 more
doaj +3 more sources
Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes [PDF]
International Journal of Medical Sciences, 2011 Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine.
Sidney J. Stohs, Harry G Preuss, Samuel C. Keith, Patti L. Keith, Howard Miller, Gilbert R. Kaats
doaj +3 more sources
Bio inspired assessment of titanium-organic framework and exosome-constructed p-Synephrine carriage: pursuing the PI3K/mTOR pathway in a simulated periodontitis [PDF]
Scientific ReportsPeriodontitis, a chronic inflammatory disease, is driven by bacterial infection and oxidative stress, leading to tissue destruction and potential tooth loss.
Mohamed S. Kishta +5 more
doaj +2 more sources
Synergistic Effect of Composite Chitosan/Phenylalanine Edible Coating on the Postharvest Bioactive Composition of Mandarin Fruit. [PDF]
Food Sci NutrChitosan/Phenylalanine (Chitosan/Phe) composite coating markedly enhanced the postharvest stability and biochemical integrity of mandarin fruit. This treatment effectively extended shelf life to 12 days at ambient conditions and 35 days under cold storage, while significantly increasing polyphenolic and flavonoid content and sustaining antioxidant ...
Jurić S +5 more
europepmc +2 more sources