Temperature Cycling Induced Deracemization of p‑Synephrine in the Presence of Degradation [PDF]
ACS OmegaThe acquisition of enantioenriched organic molecules is crucial in processes where the enantiomeric purity of active ingredients impacts efficacy and safety. Temperature cycling-induced deracemization (TCID) can achieve deracemization, but its effectiveness can be hindered by degradation reactions that influence the kinetics and the achievable ...
Po Sang Lo +2 more
doaj +6 more sources
Effects of p-synephrine in combination with caffeine: a review
Nutrition and Dietary Supplements, 2017 Sidney J Stohs,1,2 Nicholas A Ratamess3 1School of Pharmacy and Health Professions, Creighton University, Omaha, NE, 2Kitsto Consulting LLC, Frisco, TX, 3Department of Health and Exercise Science, College of New Jersey, Ewing, NJ, USA Abstract: This ...
Stohs SJ, Ratamess NA
doaj +4 more sources
Presence of p-synephrine in teas commercialized in Porto Alegre (RS/Brazil) [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2009 Citrus aurantium (bitter orange) is characterized by the presence of p-synephrine, an amine structurally and pharmacologically related to ephedrine.
Marcelo Dutra Arbo +7 more
doaj +7 more sources
Effects of p-Synephrine during Exercise: A Brief Narrative Review. [PDF]
Nutrients, 2021 The p-synephrine is the principal phytochemical found in bitter orange (Citrus aurantium). This substance is widely included in dietary supplements for weight loss/body fat reduction due to its potential benefits of increasing fat oxidation. For years, p-synephrine-containing dietary supplements have been marketed without proper knowledge of their true
Ruiz-Moreno C +4 more
europepmc +9 more sources
Effect of p-Synephrine on Fat Oxidation Rate during Exercise of Increasing Intensity in Healthy Active Women. [PDF]
Nutrients, 2022 p-Synephrine is the principal alkaloid of bitter orange (Citrus aurantium). Several recent investigations have found that the intake of 2–3 mg/kg of p-synephrine raises fat oxidation rate during exercise of low-to-moderate intensity. However, these investigations have been carried out only with samples of male participants or mixed men/women samples ...
Gutiérrez-Hellín J +8 more
europepmc +9 more sources
The Safety and Efficacy of Citrus aurantium (Bitter Orange) Extracts and p-Synephrine: A Systematic Review and Meta-Analysis. [PDF]
Nutrients, 2022 Synephrine has been used to promote weight loss; however, its safety and efficacy have not been fully established. The goals of our study were to give an overview of the safety and efficacy of p-synephrine, to systematically evaluate its efficacy regarding weight loss and to assess its safety, focusing on its cardiovascular side effects in a meta ...
Koncz D +4 more
europepmc +7 more sources
Citrus p-Synephrine Improves Energy Homeostasis by Regulating Amino Acid Metabolism in HFD-Induced Mice. [PDF]
Nutrientsp-Synephrine is a common alkaloid widely distributed in citrus fruits. However, the effects of p-synephrine on the metabolic profiles of individuals with energy abnormalities are still unclear. In the study, we investigated the effect of p-synephrine on energy homeostasis and metabolic profiles using a high fat diet (HFD)-induced mouse model.
Bai J +6 more
europepmc +4 more sources
p‐Synephrine, ephedrine, p‐octopamine and m‐synephrine: Comparative mechanistic, physiological and pharmacological properties [PDF]
Phytotherapy Research, 2020 AbstractConfusion and misunderstanding exist regarding the lack of cardiovascular and other adverse health effects of p‐synephrine and p‐octopamine relative to ephedrine and m‐synephrine (phenylephrine) which are known for their effects on the cardiovascular system. These four molecules have some structural similarities.
Sidney J Stohs +2 more
exaly +5 more sources
Phytochemical Combination (p-Synephrine, p-Octopamine Hydrochloride, and Hispidulin) for Improving Obesity in Obese Mice Induced by High-Fat Diet. [PDF]
Nutrients, 2022 Obesity treatment efficiency can be increased by targeting both central and peripheral pathways. In a previous study, we identified two natural compounds (hispidulin and p-synephrine) that affect adipocyte differentiation. We tested whether obesity treatment efficiency may be improved by adding an appetite-controlling agent to the treatment in the ...
Lee D +5 more
europepmc +4 more sources
Acute p-synephrine ingestion increases whole-body fat oxidation during 1-h of cycling at Fatmax [PDF]
European Journal of Nutrition, 2019 p-Synephrine, the principal alkaloid of bitter orange (Citrus aurantium), is widely used in dietary supplements for weight loss due to its purported effect of increasing fat oxidation. However, there is a paucity of scientific information about its effectiveness in enhancing fat oxidation during exercise.
Jorge Gutiérrez-Hellín +2 more
core +7 more sources