FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Do we focus on process over outcome? Review of published studies in two prominent saudi journals
Cogent EducationIt is well-known that published science is judged by the judicious and careful use of methods employed when acquiring knowledge and understanding. However, since the beginning of the millennia, concerns over the validity and reliability of scientific ...
Ruwayshid Alruwaili
doaj +1 more source
Value sharing problem and uniqueness for p-adic meromorphic functions and their derivatives [PDF]
, 2012 Hà Huy Khoái +2 more
openalex +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
HUBUNGAN FAKTOR MATERNAL DAN PERAWATAN BAYI DENGAN KEMATIAN NEONATAL PADA KELUARGA MISKIN DI KABUPATEN PADANG PARIAMAN TAHUN 2004 (RELATION OF MATERNAL FACTOR AND BABY NURSING WITH DEATH OF NEONATAL AT IMPECUNIOUS FAMILY OF YEAR 2004) [PDF]
, 2005 Kematian bayi merupakan indikator utama dalam pembangunan kesehatan. 50% Angka Kematian Bayi terdiri dari Angka Kematian Neonatal. Di Kabupaten Padang Pariaman Angka Kematian Bayi sebesar 1,9%, 87,9% dari kematian bayi berasal dari neonatal, dan 75,2 ...
YANDRIDA, ROSLIDAR
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Frontiers in Veterinary ScienceVeterinarians in all settings strive to practice evidence-based medicine, but current methods of reporting scientific study results create barriers to clinical translation of findings.
Brenna R. Pugliese +12 more
doaj +1 more source
Clinical relevance of a p value: Does tranexamic acid save lives after trauma or postpartum hemorrhage? [PDF]
, 2017 Geoffrey P. Dobson +2 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source