Results 111 to 120 of about 34,114,673 (279)
Shareholder value creators in the S&P 500: Year 2004 [PDF]
During 2004, 64% of the companies in the S&P 500 created value, while in 2003 the figure was 87%. The market value of the 500 companies was $11.2 trillion in 2004, compared to $10.1 trillion in 2003. The top shareholder value creators in 2004 were Exxon,
Villanueva, Alvaro, Fernandez, Pablo
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Frontiers in Applied Mathematics and StatisticsThere has been an important move away from the term “statistical significance” in the scientific and statistical community. The desire to “retire 0.05” is rooted in improving scientific reporting by ensuring that researchers report more information than ...
Brian C. Healy +2 more
doaj +1 more source
Are realized volatility models good candidates for alternative Value at Risk prediction strategies? [PDF]
In this paper, we assess the Value at Risk (VaR) prediction accuracy and efficiency of six ARCH-type models, six realized volatility models and two GARCH models augmented with realized volatility regressors.
Refenes, Apostolos P. +2 more
core
, 2012 By using critical point theory, we establish the existence of infinitely many weak solutions for a class of elliptic Navier boundary value problems depending on two parameters and involving the p-biharmonic operator. © 2012 Elsevier Ltd.
Livrea, R., Candito, P., Li, L.
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Response Surface Methodology Optimization of Wear Rate Parameters in Metallic Alloys
ABUAD Journal of Engineering Research and DevelopmentThe optimization of wear rate parameters in metallic alloys using Response Surface Methodology (RSM) has been experimentally performed. The wear rate, a critical factor affecting the durability and performance of metallic components, served as the ...
Blessing Ngozi Goodluck Aliemeke +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Recognition of cancer mediating genes using MLP-SDAE model
Systems and Soft ComputingThis article introduces a predictive deep learning model called MLP-SDAE, which combines Multilayer Perceptron (MLP) and Stacked Denoising Auto-encoder (SDAE) techniques.
Sougata Sheet +2 more
doaj +1 more source