Results 151 to 160 of about 7,087,225 (342)

Cultural and economic value: A (p)review

open access: gold, 2017
Francesco Angelini   +1 more
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Building a Predictive Model for Predicting Real Estate Prices Based on the Generated Database

open access: yesRUDN Journal of Engineering Research
The work is devoted to solving the current problem of forecasting real estate prices by building a predictive model based on the generated database of real estate in Moscow, posted on the Move Real Estate website.
Polina A. Konyaeva   +2 more
doaj   +1 more source

A new approach for approximating the p-value of a class of bivariate sign tests. [PDF]

open access: yesSci Rep, 2023
Shanan IAA   +2 more
europepmc   +1 more source

P-065 Prognostic value of carbohydrate tumor markers and inflammation-based markers in gastric cancer [PDF]

open access: bronze, 2015
Weiwei Kong   +6 more
openalex   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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