Results 91 to 100 of about 32,868,481 (282)
Two P or Not Two P: Mendel Random Variables in Combining Fake and Genuine p-Values
AppliedMathThe classical tests for combining p-values use suitable statistics T(P1,…,Pn), which are based on the assumption that the observed p-values are genuine, i.e., under null hypotheses, are observations from independent and identically distributed Uniform(0 ...
M. Fátima Brilhante +4 more
doaj +1 more source
Why, When and How to Adjust Your P Values?
Cell Journal, 2019 Currently, numerous papers are published reporting analysis of biological data at different omics levels by making statistical inferences. Of note, many studies, as those published in this Journal, report association of gene(s) at the genomic and ...
Mohieddin Jafari, Naser Ansari-Pour
doaj +1 more source
Statistics instructors’ beliefs and misconceptions about p-values
, 2017 It is well known that students of inferential statistics find the hypothetical, probabilistic reasoning used in hypothesis tests difficult to understand. Consequently, they will also have difficulties in understanding p-values.
Robyn Reaburn (14747638)
core
Source codes for obtaining CHD gene association P-values
, 2017 <p>This includes source codes to obtain gene association P-values from the CHD sequencing data.</p ...
Lin, Lin (8099927)
core +1 more source
p-values for Pearson correlations between years.
, 2023 In bold are p-values ≥0.05 (no statistically significant correlation).
Héctor Sánchez-Delgado (15999078) +1 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Not p-Values, Said a Little Bit Differently
Econometrics, 2019 As a contribution toward the ongoing discussion about the use and mis-use of p-values, numerical examples are presented demonstrating that a p-value can, as a practical matter, give you a really different answer than the one that you want.
Richard Startz
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source