Results 101 to 110 of about 32,868,481 (282)

S-values and Surprisal intervals to Replace P-values and Confidence Intervals

open access: yesRevstat Statistical Journal
Misuse of statistical significance continues to be prevalent in science. The absence of intuitive explanations of this concept often leads researchers to incorrect conclusions.
Alessandro Rovetta
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

P-wave measurements and reference values.

open access: yes, 2018
P-wave measurements and reference values.
Wilson Nadruz Jr (493440)   +10 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Effects of Different Contact Lens Designs on Visual Quality Among the Soft Spherical Contact Lens Users

open access: yesTürk Oftalmoloji Dergisi, 2013
Purpose: To evaluate the effects of different lens designs on visual quality among soft spherical contact lens users. Material and Method: Forty eyes of twenty patients from our contact lens unit were included in this study.
Mustafa Demir   +2 more
doaj   +1 more source

Understanding significance and p-values

open access: yesNepal Journal of Epidemiology, 2016
<p>Since the p-value is a single index, following the ASA’s statement, we strongly support that it cannot and should not be considered as the sole basis for scientific reasoning. Given the misuses and misconceptions concerning p-values, the recommendation is to present the estimate of the effect, provide a measure of uncertainty of the estimation
openaire   +3 more sources

P values in display items are ubiquitous and almost invariably significant: A survey of top science journals [PDF]

open access: yes, 2018
P values represent a widely used, but pervasively misunderstood and fiercely contested method of scientific inference. Display items, such as figures and tables, often containing the main results, are an important source of P values.
Ioana Alina Cristea (5220806)   +6 more
core   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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