Results 161 to 170 of about 21,046,542 (243)
, 2007 In an attempt to describe the nature of recent journal literature revolving around the eleven core values of librarianship, as articulated by the American Library Association, this exploratory study analyzed 114 articles from four peer-reviewed library ...
Rebecca K. Miller, Core Values
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Effectiveness of a Values Education Program for Preschool Students: A Teacher-Based Evaluation Study
The purpose of this study is to investigate the effectiveness of the Preschool Values Education Program, which was developed in line with the values identified through a needs analysis and prepared in accordance with the Taba Curriculum Development Model.
Kayıran, Derya, Bağçeci, Birsen
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Recent Trend and Further Direction of Studies on Values
, 1998 Although values are an important determinant of human behavior, not much attention have been paid to values. In this article, recent studies suggesting the importance and uniqueness of value scales were reviewed. First, the author adopt Rokeach's view of
HIROSE, Haruji +2 more
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Values for Peace: Ethnographic Lessons From the Semaiof Malaysia and the Mardu of Australia
, 2010 Schwartz’s model of basic human values conceptualizes self-enhancing and selftranscendenceas opposing value dimensions. Self-enhancing values include striving forpower and achievement; hence, they are individual-centric, whereas self-transcendencevalues ...
Fry, Douglas P.,, Miklikowska, Marta,
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source