Results 61 to 70 of about 21,046,542 (243)

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

The assessment of replicability using the sum of p-values

Royal Society Open Science
Statistical significance of both the original and the replication study is a commonly used criterion to assess replication attempts, also known as the two-trials rule in drug development.
Leonhard Held, Samuel Pawel, Charlotte Micheloud   +2 more
doaj   +1 more source

Haematological values of three Antarctic penguins: gentoo (Pygoscelis papua), Adélie (P. adeliae) and chinstrap (P. antarcticus) [PDF]

Polar Research, 2015
It is established that haematological and biochemical parameters provide important data to assess the physiological condition and health status of wild birds.
Andrés E. Ibañez, Roberto Najle, Karen Larsen, Marcela Pari, Amalia Figueroa, Diego Montalti   +5 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Crouching learners, hidden values: values in school mathematical literacy lessons [PDF]

, 2012
Philosophiae Doctor - PhDLocal and international pundits concur that education systems play a pivotal role in fostering and developing values in learners.
Rughubar-Reddy, Sheena
core   +1 more source

New relevance and significance measures to replace p-values.

PLoS ONE, 2021
The p-value has been debated exorbitantly in the last decades, experiencing fierce critique, but also finding some advocates. The fundamental issue with its misleading interpretation stems from its common use for testing the unrealistic null hypothesis ...
Werner A Stahel
doaj   +1 more source

P-values of statistical tests for stationarity.

, 2022
P-values of statistical tests for stationarity.
Seyed Iman Mohammadpour (13977640), Mohammad Dahaghin (13977643), Habibollah Nassiri (13977637)   +2 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Comparative study of threshold selection methods in the generalised Pareto distribution with application to rainfall datasets

Data Analytics and Applied Mathematics
Extreme rainfall events pose significant challenges for flood risk management and infrastructure planning, necessitating robust statistical tools for accurate risk assessment.
Farabe Khan Alif, Norhaslinda Ali
doaj   +1 more source