Results 51 to 60 of about 42,945,447 (298)
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Determination of p-y curves for offshore piles based on in-situ soil investigations
Offshore piles are subjected to complex loads with considerable lateral component. The pile-soil response to lateral loads can be described with the p-y method.
Międlarz Kamila, Bałachowski Lech
doaj +1 more source
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
Impact of soil-conductor p-y curves on fatigue life assessment of offshore drilling systems
During subsea drilling campaigns, the conductor is the outermost pipe of the well in contact with the soil near the seabed. It is used to prevent the walls of the borehole from collapsing and to provide axial support to the structure. While drilling, the
Doherty, J. +5 more
core +1 more source
A new p-y model for soil-pile interaction analyses in cohesionless soils under monotonic loading
The most widely used analysis method for the laterally loaded pile problem is the Winkler spring approach. Although researchers have proposed nonlinear formulations for the p-y curves, the contribution of the soil nonlinearity has not been thoroughly ...
Ozan Alver, E. Ece Eseller-Bayat
doaj +1 more source
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine +21 more
wiley +1 more source
Modern offshore wind turbines require increasingly larger monopile foundations, often with low embedded length-to-diameter ratios that fall outside the calibration range of the conventional standard p–y approach.
Ali Khezri, Hongbae Park, Daeyong Lee
doaj +1 more source
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source
TORSION OF ELLIPTIC CURVES OVER QUADRATIC CYCLOTOMIC FIELDS [PDF]
In this paper we study the possible torsions of elliptic curves over ℚ(i) and ℚ(√−3)
Najman, Filip, Filip Najman
core +1 more source

