Results 241 to 250 of about 24,223,577 (293)

Low concentrations of tetrasodium EDTA cause significant killing of biofilm-associated P. aeruginosa in high validity models of chronic wound and CF lung infections – but not in a model of endotracheal tube colonisation

Orababa OQ, Cornbill C, Kade A, Reddy N, Gulati R, Harrison F.   +5 more
europepmc   +1 more source

Acetylation of alginate enables the production of inks that mimic the chemical properties of P. aeruginosa biofilm.

J Mater Chem B
Schandl S, Osondu-Chuka G, Guagliano G, Perak S, Petrini P, Briatico-Vangosa F, Reimhult E, Guillaume O.   +7 more
europepmc   +1 more source

P. aeruginosa Biofilms in CF Infection [PDF]

Clinical Reviews in Allergy and Immunology, 2008
Pseudomonas aeruginosa is an opportunistic pathogen of immunocompromised hosts. In cystic fibrosis (CF), P. aeruginosa causes acute and chronic lung infections that result in significant morbidity and mortality. P. aeruginosa possesses several traits that contribute to its ability to colonize and persist in acute and chronic infections.
Victoria E Wagner, Barbara H Iglewski
exaly   +3 more sources

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Nanoscale effects of antibiotics on P. aeruginosa

Nanomedicine: Nanotechnology, Biology and Medicine, 2012
Studying living bacteria at the nanoscale in their native liquid environment opens an unexplored landscape. We focus on Pseudomonas aeruginosa and demonstrate how the cell wall is biophysically affected at the nanoscale by two reference antibiotics (ticarcillin and tobramycin).
Formosa-Dague, Cécile, Grare, Marion, Duval, Raphaël E., Dague, Etienne   +3 more
openaire   +4 more sources

P. aeruginosa quorum-sensing systems and virulence

Current Opinion in Microbiology, 2003
Quorum sensing is an important mechanism for the regulation of genes in many Gram-negative and Gram-positive bacteria. In the opportunistic pathogen Pseudomonas aeruginosa, the absence of one or more components of the quorum-sensing system results in a significant reduction in virulence.
Roger S, Smith, Barbara H, Iglewski
openaire   +2 more sources

P. aeruginosa biofilm activates the NLRP3 inflammasomes in vitro

Microbial Pathogenesis, 2022
The ability of P.aeruginosa to form biofilms renders common treatments inefficient, thereby promoting chronic infection. Inflammasomes activate caspase-1, which is important for the maturation of IL-1β and IL-18 and evoke an inflammatory response. We aimed to investigate the activation of inflammasomes induced by P.aeruginosa biofilm.
Qi, Tan, Qing, Ai, Yu, He, Fang, Li, Jialin, Yu   +4 more
openaire   +2 more sources

Acquired Resistance to P. aeruginosa

1993
Infections due to Pseudomonas aeruginosa are difficult to acquire without a basic underlying condition such as immunosuppression or cystic fibrosis (CF). Innate resistance to this organism is high. Community-acquired infection is rare, limited mostly to non-life-threatening conditions such as folliculitis from a hot tub or whirlpool and otitis externa.
openaire   +1 more source