Results 1 to 10 of about 11,948,174 (351)

Identification of Biomarkers for Differentiation of Hypervirulent Klebsiella pneumoniae from Classical K. pneumoniae [PDF]

Journal of Clinical Microbiology, 2018
A hypervirulent Klebsiella pneumoniae (hvKp) pathotype is undergoing global dissemination. In contrast to the usual health care-associated epidemiology of classical K.
T. Russo, R. Olson, C. Fang, N. Stoesser, Mark A. Miller, U. MacDonald, A. Hutson, Jason H. Barker, R. L. La Hoz, James R. Johnson   +9 more
semanticscholar   +3 more sources

Autophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectives. [PDF]

Emerg Microbes Infect, 2023
Klebsiella pneumoniae is a notorious nosocomial pathogen causing a wide range of infections. The increasing trend of antimicrobial resistance obtained by the species immensely highly challenges the clinical treatment, representing a large threat to the ...
Wei S, Xu T, Chen Y, Zhou K.
europepmc   +2 more sources

Assessment of antimicrobial combinations for Klebsiella pneumoniae carbapenemase-producing K. pneumoniae. [PDF]

The Journal of Infectious Diseases, 2013
The prevalence of bla(KPC) among gram-negative bacteria continues to increase worldwide. Limited treatment options exist for this multidrug-resistant phenotype, often necessitating combination therapy. We investigated the in vitro and in vivo efficacy of multiple antimicrobial combinations.Two clinical strains of Klebsiella pneumoniae carbapenemase ...
Elizabeth B. Hirsch, Beining Guo, Kai-tai Chang, Henry Cao, K. R. Ledesma, Manisha Singh, V. Tam   +6 more
semanticscholar   +3 more sources

Risk Factors and Clinical Impact of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae [PDF]

Infection Control & Hospital Epidemiology, 2009
Background.Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae is an emerging pathogen with serious clinical and infection control implications. To our knowledge, no study has specifically examined risk factors for KPC-producing K. pneumoniae or its impact on mortality.Methods.To identify risk factors for infection or colonization with ...
L. Gasink, P. Edelstein, E. Lautenbach, M. Synnestvedt, N. Fishman   +4 more
semanticscholar   +3 more sources

Hypervirulent K. Pneumoniae Secretes More and More Active Iron-Acquisition Molecules than “Classical” K. Pneumoniae Thereby Enhancing its Virulence

PLoS ONE, 2011
Background A new hypervirulent (hypermucoviscous) clinical variant of Klebsiella pneumoniae (hvKP) has emerged over the last decade. Our goal is to identify new mechanisms, which increase the virulence hvKP compared to “classic” K.
T. Russo, A. Shon, J. Beanan, R. Olson, U. MacDonald, A. Pomakov, M. Visitacion   +6 more
semanticscholar   +5 more sources

High prevalence of Klebsiella pneumoniae carbapenemase-mediated resistance in K. pneumoniae isolates from Egypt.

Eastern Mediterranean Health Journal, 2013
The emergence and rapid spread of antibiotic-resistant Klebsiella pneumoniae isolates harbouring the blaKPC gene that encodes for carbapenemase production have complicated the management of patient infections. This study in a tertiary care hospital in Egypt used real-time PCR assay to test ertapenem-nonsusceptible isolates of K.
L. Metwally, N. Gomaa, M. Attallah, N. Kamel   +3 more
semanticscholar   +3 more sources

Prevalence assessment of magA gene and antimicrobial susceptibility of Klebsiella pneumoniae isolated from clinical specimens in Shahrekord, Iran [PDF]

Iranian Journal of Microbiology, 2014
Background and Objectives: Klebsiella pneumoniae (K. pneumoniae) is an opportunistic microorganism. This study aimed to investigate the presence of magA gene and antimicrobial susceptibility in K. pneumoniae. Materials and Methods: 195 clinical specimens
Hadis Amraie, Pegah Shakib, Samaneh Rouhi, Neda Bakhshandeh, Behnam Zamanzad   +4 more
doaj   +2 more sources

Clinical Characteristics of K. pneumoniae Related Endogenous Endophthalmitis in China. [PDF]

Risk Manag Healthc Policy
To investigate the clinical characteristics and systemic risk factors of K. pneumoniae related endogenous endophthalmitis (KPREE) in China and explore the possible pathophysiological mechanisms.This was a retrospective comparative study. All enrolled KPREE patients were followed up for at least 1 month to observe their clinical characteristics ...
Wang X, Song Y, Ji Y, Chen A, Si S.
europepmc   +4 more sources

Pyroptosis, apoptosis, and autophagy are involved in infection induced by two clinical Klebsiella pneumoniae isolates with different virulence

Frontiers in Cellular and Infection Microbiology, 2023
Klebsiella pneumoniae can cause widespread infections and is an important factor of hospital- and community-acquired pneumonia. The emergence of hypervirulent K.
Xueting Wang, Chunxia Bi, Xiaoni Xin, Mengmeng Zhang, Hengxia Fu, Lei Lan, Mengyuan Wang, Zhiyong Yan   +7 more
doaj   +1 more source

Prevalence and incidence of carbapenem-resistant K. pneumoniae colonization: systematic review and meta-analysis

Systematic Reviews, 2022
Background Klebsiella pneumoniae is a gram-negative rod belonging to the order Enterobacterales and having a wide distribution in the environment, including the human colon.
Tewodros Tesfa, H. Mitiku, M. Edae, N. Assefa   +3 more
semanticscholar   +1 more source