Results 1 to 10 of about 121,727 (164)

Identification of Biomarkers for Differentiation of Hypervirulent Klebsiella pneumoniae from Classical K. pneumoniae [PDF]

Journal of Clinical Microbiology, 2018
A hypervirulentKlebsiella pneumoniae(hvKp) pathotype is undergoing global dissemination. In contrast to the usual health care-associated epidemiology of classicalK. pneumoniae(cKp) infections, hvKp causes tissue-invasive infections in otherwise healthy individuals from the community, often involving multiple sites.
Thomas A Russo, Ruth Olson, Chi-Tai Fang   +2 more
exaly   +3 more sources

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology, 2018
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae strains into opportunistic, hypervirulent, and multidrug-resistant groups and separates
Rebekah M Martin, Michael A Bachman
exaly   +3 more sources

Virulence Factors and Antibiotic Resistance of Klebsiella pneumoniae Strains Isolated From Neonates With Sepsis

Frontiers in Medicine, 2018
Introduction:Klebsiella pneumoniae is one of the most important infectious agents in neonates. There are “classic” and hypervirulent strains of K. pneumoniae. The “classic” non-virulent strain of K. pneumoniae, producing extended-spectrum beta-lactamases
V A Anokhin, Albert A Rizvanov, Yuriy Davidyuk   +2 more
exaly   +3 more sources

Clinical Characteristics of K. pneumoniae Related Endogenous Endophthalmitis in China. [PDF]

Risk Manag Healthc Policy
To investigate the clinical characteristics and systemic risk factors of K. pneumoniae related endogenous endophthalmitis (KPREE) in China and explore the possible pathophysiological mechanisms.This was a retrospective comparative study. All enrolled KPREE patients were followed up for at least 1 month to observe their clinical characteristics ...
Wang X, Song Y, Ji Y, Chen A, Si S.
europepmc   +5 more sources

The Characteristic of Biofilm Formation in ESBL-Producing K. pneumoniae Isolates. [PDF]

Can J Infect Dis Med Microbiol
Klebsiella pneumoniae is a pathogen that commonly causes hospital‐acquired infections. Bacterial biofilms are structured bacterial communities that adhere to the surface of objects or biological tissues. In this study, we investigated the genome homology and biofilm formation capacity of ESBL‐producing K. pneumoniae. Thirty ESBL‐producing K. pneumoniae
Gao X, Wang H, Wu Z, Sun P, Yu W, Chen D, Mao Y, Fang L, Qian J, Li L, Peng Q, Han Y.   +11 more
europepmc   +4 more sources

Pyroptosis, apoptosis, and autophagy are involved in infection induced by two clinical Klebsiella pneumoniae isolates with different virulence

Frontiers in Cellular and Infection Microbiology, 2023
Klebsiella pneumoniae can cause widespread infections and is an important factor of hospital- and community-acquired pneumonia. The emergence of hypervirulent K.
Xueting Wang, Chunxia Bi, Xiaoni Xin, Mengmeng Zhang, Hengxia Fu, Lei Lan, Mengyuan Wang, Zhiyong Yan   +7 more
doaj   +1 more source

One-Pot Isothermal LAMP-CRISPR-Based Assay for Klebsiella pneumoniae Detection

Microbiology Spectrum, 2022
Klebsiella pneumoniae (K. pneumoniae) is one of the most common pathogens causing nosocomial infection. A rapid, accurate, and convenient detection method is required for early diagnosis and directed therapy of K. pneumoniae infection. CRISPR-top (CRISPR-
Xiaotong Qiu, Xueping Liu, Xiao Ma, Ruixue Wang, Shenglin Chen, Fang Li, Zhenjun Li   +6 more
doaj   +1 more source

A Novel Peptide as a Specific and Selective Probe for Klebsiella pneumoniae Detection

Biosensors, 2022
Klebsiella pneumoniae is infamous for generating hospital-acquired infections, many of which are difficult to treat due to the bacterium’s multidrug resistance. A sensitive and robust detection method of K. pneumoniae can help prevent a disease outbreak.
Hyun Kim, Ju Hye Jang, In Young Jung, Ju Hyun Cho   +3 more
doaj   +1 more source

Assessment of Antimicrobial Combinations for Klebsiella pneumoniae Carbapenemase–Producing K. pneumoniae [PDF]

The Journal of Infectious Diseases, 2012
The prevalence of bla(KPC) among gram-negative bacteria continues to increase worldwide. Limited treatment options exist for this multidrug-resistant phenotype, often necessitating combination therapy. We investigated the in vitro and in vivo efficacy of multiple antimicrobial combinations.Two clinical strains of Klebsiella pneumoniae carbapenemase ...
Elizabeth B, Hirsch, Beining, Guo, Kai-Tai, Chang, Henry, Cao, Kimberly R, Ledesma, Manisha, Singh, Vincent H, Tam   +6 more
openaire   +2 more sources

Effects of gallic acid on capsular polysaccharide biosynthesis in Klebsiella pneumoniae

Journal of Microbiology, Immunology and Infection, 2022
Background: Klebsiella pneumoniae is a gram-negative opportunistic pathogen that causes diseases mostly in immunocompromised individuals. Recently, hypervirulent K. pneumoniae strains also cause severe disease in healthy individuals.
Tien-Huang Lin, Chien-Chen Wu, Cheng-Yin Tseng, Jing-Han Fang, Ching-Ting Lin   +4 more
doaj   +1 more source