Results 31 to 40 of about 9,296,418 (261)

Clinical Observation and Prognostic Analysis of Patients With Klebsiella pneumoniae Bloodstream Infection

Frontiers in Cellular and Infection Microbiology, 2020
Background and purposeThe clinical prognosis of Klebsiella pneumoniae(K. pneumoniae) bloodstream infection is poor, and the prevalence of drug-resistant bacteria makes clinical anti-infective treatment more challenging. This retrospective study evaluated
Shuguang Zhang, Ziyue Yang, Limin Sun, Zhenhua Wang, Liutao Sun, Liutao Sun, Jinli Xu, Jinli Xu, Li Zeng, Tongwen Sun   +9 more
doaj   +1 more source

Host defense against the infection of Klebsiella pneumoniae: New strategy to kill the bacterium in the era of antibiotics?

Frontiers in Cellular and Infection Microbiology, 2022
Klebsiella pneumoniae (K. pneumoniae) is a typical gram-negative iatrogenic bacterium that often causes bacteremia, pneumonia and urinary tract infection particularly among those with low immunity.
Zihan Liang, Zihan Liang, Zihan Liang, Yiyao Wang, Yiyao Wang, Yiyao Wang, Yixiang Lai, Yixiang Lai, Yixiang Lai, Jingyi Zhang, Jingyi Zhang, Jingyi Zhang, Lanlan Yin, Lanlan Yin, Lanlan Yin, Xiang Yu, Xiang Yu, Xiang Yu, Yongqin Zhou, Yongqin Zhou, Yongqin Zhou, Xinzhi Li, Xinzhi Li, Yinhong Song, Yinhong Song, Yinhong Song   +25 more
doaj   +1 more source

Fecal shedding of Klebsiella pneumoniae by dairy cows [PDF]

, 2006
Klebsiella pneumoniae is a common cause of clinical mastitis in dairy cattle. Wood products are considered to be the main source of Klebsiella on dairy farms.
Rauch, B.J., Zadoks, R. N., Munoz, M. A., Ahlström, C., Zadoks, R.N., Munoz, M.A., Rauch, B. J.   +6 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The identification of Streptococcus pneumoniae [PDF]

, 2006
ei tietoa saavutettavuudesta unknown ...
Kaijalainen, Tarja
core  

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates. [PDF]

, 2012
Contains fulltext : 110162.pdf (Publisher’s version ) (Closed access)The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and
Bentley, S.D., Hinds, J., Lambertsen, L., Bootsma, H. J., Hermans, PW, Bentley, SD, Hanage, WP, Antonio, M., Hermans, P.W.M., O'Brien, K. L., Turner, P, Hanage, William, Antonio, M, Salter, S. J., Bentley, S. D., Hermans, P. W. M., Gould, KA, Turner, P., Gould, K.A., Bootsma, H.J., Turner, Paul, Gould, K. A., O'Brien, KL, Salter, S.J., Salter, SJ, Bootsma, HJ, Lambertsen, L, Hinds, J, O'Brien, K.L., Hanage, W.P.   +29 more
core   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Convergence of carbapenem resistance and hypervirulence leads to high mortality in patients with postoperative Klebsiella pneumoniae meningitis

Journal of Global Antimicrobial Resistance, 2021
: Objectives: The aims of this study were to investigate the characteristics of Klebsiella pneumoniae meningitis and the impact of convergence of carbapenem resistance and hypervirulence on patient mortality.Methods: Antimicrobial resistance and ...
Yuming Li, Dakang Hu, Xiaobo Ma, Dan Li, Dongxing Tian, Ye Gong, Xiaofei Jiang   +6 more
doaj   +1 more source

Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo [PDF]

, 2012
Lipoproteins are an important class of surface associated proteins that have diverse roles and frequently are involved in the virulence of bacterial pathogens.
Hermans Peter W. M., Brown, J.S., Durmort Claire, Jeremy S. Brown, Jonathan M Cohen, Emilie Camberlein, Hermans, P.W.M., Camberlein Emilie, Durmort, C, Vernet Thierry, MacDonald, N, Chimalapati, S, Claire Durmort, Jeremy S Brown, Timothy Mitchell, Suneeta Chimalapati, Cohen, J.M., Camberlein, E, Peter W. M. Hermans, Brown, JS, Chimalapati, S., Hermans, PWM, Vernet, T., Chimalapati Suneeta, Camberlein, E., Mitchell, T., Mitchell Timothy, MacDonald, N., Peter W M Hermans, Nathanael MacDonald, Thierry Vernet, Vernet, T, Cohen, JM, Cohen Jonathan M., Brown Jeremy S., MacDonald Nathanael, Durmort, C., Jonathan M. Cohen, Mitchell, T   +38 more
core   +3 more sources