The Difficult Case of Crystallization and Structure Solution for the ParC55 Breakage-Reunion Domain of Topoisomerase IV from Streptococcus pneumoniae. [PDF]
BACKGROUND: Streptococcus pneumoniae is the major cause of community-acquired pneumonia and is also associated with bronchitis, meningitis, otitis and sinusitis.
Laponogov, I +17 more
core +1 more source
Antibiotic sensitivity screening of Klebsiella spp. and Raoultella spp. isolated from marine bivalve molluscs reveal presence of CTX-M-producing K. pneumoniae [PDF]
Klebsiella spp. are a major cause of both nosocomial and community acquired infections, with K. pneumoniae being responsible for most human infections. Although Klebsiella spp.
Marit A. K. Hetland +11 more
core +1 more source
Abdominal surgical site infection due to Klebsiella pneumoniae carbapenemase‐producing K. pneumoniae
.The spread of bacteria extensively resistant to multiple antibiotics is becoming an unprecedented public health concern. Different from multidrug-resistant (MDR) Gram-positive pathogens, for which new antibiotics (such as new glycopeptides and oxazolidinones) have already been approved in virtue of high efficacy, the situation surrounding MDR Gram ...
VIRGILIO, EDOARDO +4 more
openaire +5 more sources
A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting. [PDF]
A 10-month longitudinal household study of pre-school children and their families was undertaken with monthly visits collecting epidemiological data and nasopharyngeal swabs in Hertfordshire, England from 2001 to 2002.
Martin, SA +8 more
core +1 more source
Антибактериальная терапия госпитальных инфекций, вызванных карбапенемазопродуцирующими штаммами K. pneumoniae [PDF]
ИНФЕКЦИЯ ВНУТРИБОЛЬНИЧНАЯБОЛЬНИЧНАЯ ИНФЕКЦИЯВНУТРИГОСПИТАЛЬНАЯ ИНФЕКЦИЯНОЗОКОМИАЛЬНАЯ ИНФЕКЦИЯПЕРЕКРЕСТНАЯ ИНФЕКЦИЯKLEBSIELLA PNEUMONIAEKLEBSIELLA PNEUMONIAE SCHROETERKLEBSIELLA RHINOSCLEROMATISЛЕКАРСТВЕННАЯ УСТОЙЧИВОСТЬ У МИКРООРГАНИЗМОВРЕЗИСТЕНТНОСТЬ К
Жильцов, И. В. +2 more
core +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
A simple, rapid, and portable gold‐coated filter tip‐based assay (GFTA) is developed for bacterial detection. The GFTA leverages cleavable functional nucleic acid probes as molecular recognition elements to target RNase H2, a highly conserved bacterial endoribonuclease, enabling sensitive and specific colorimetric detection of bacterial pathogens ...
Jiuxing Li +4 more
wiley +2 more sources
The emergence of Klebsiella pneumoniae carbapenemase (KPC) resistance has led to the countdown of activity of carbapenems, which were considered as drugs of last resort for infections caused by Enterobacteriaceae. The aims of the present study were the detection of KPC-production among K.
Azam Shahi +7 more
openaire +2 more sources
Seasonality and outbreak of a predominant Streptococcus pneumoniae serotype 1 clone from The Gambia: expansion of ST217 hypervirulent clonal complex in West Africa. [PDF]
BACKGROUND: Streptococcus pneumoniae serotype 1 causes > 20% of invasive disease, among all age groups combined, in The Gambia. In contrast, it is rarely detected in carriage studies. This study compares the molecular epidemiology of S.
Greenwood, Brian M +47 more
core +1 more source
Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu +19 more
wiley +1 more source

