Results 21 to 30 of about 11,948,174 (351)

Multidrug-resistant Klebsiella pneumoniae from clinical isolates at dr. Soeradji Tirtonegoro central hospital Klaten

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2020
Background: Klebsiella pneumoniae is a Gram-negative bacterium that often causes nosocomial infections. Use of broad-spectrum antibiotics as an empiric therapy has contributed to increases of K.
Handi Virawan, Titik Nuryastuti, Hera Nirwati   +2 more
doaj   +1 more source

Hypervirulent Klebsiella pneumoniae is emerging as an increasingly prevalent K. pneumoniae pathotype responsible for nosocomial and healthcare-associated infections in Beijing, China

Virulence, 2020
Objectives Hypervirulent Klebsiella pneumoniae(hvKp) is an increasingly important pathogen. Tracking its epidemiology and evolving antimicrobial resistance will facilitate care. Methods A retrospective study was conducted in two hospitals.
Chao Liu, P. Du, Nan Xiao, Fansen Ji, T. Russo, Jun Guo   +5 more
semanticscholar   +1 more source

Virulence Determinants of Colistin-Resistant K. pneumoniae High-Risk Clones [PDF]

Biology, 2021
We proposed the hypothesis that high-risk clones of colistin-resistant K. pneumoniae (ColR-Kp) possesses a high number of virulence factors and has enhanced survival capacity against the neutrophil activity. We studied virulence genes of ColR-Kp isolates and neutrophil response in 142 patients with invasive ColR-Kp infections.
Ozlem Dogan, Cansel Vatansever, Nazli Atac, Ozgur Albayrak, Sercin Karahuseyinoglu, Ozgun Ekin Sahin, Bilge Kaan Kilicoglu, Atalay Demiray, Onder Ergonul, Mehmet Gönen, Fusun Can   +10 more
openaire   +5 more sources

Convergence of carbapenem resistance and hypervirulence in a highly-transmissible ST11 clone of K. pneumoniae: An epidemiological, genomic and functional study

Virulence, 2020
Co-occurrence of hypervirulence and KPC-2 carbapenem resistant phenotypes in a highly-transmissible ST11 clone ofKlebsiella pneumoniae has elicited deep concerns from public health stand point.
Ping Li, Qiqiang Liang, Wu Liu, B. Zheng, Lizhang Liu, Wei Wang, Zhijiang Xu, Man Huang, Youjun Feng   +8 more
semanticscholar   +1 more source

The Influence of Biofilms on Carbapenem Susceptibility and Patient Outcome in Device Associated K. pneumoniae Infections: Insights Into Phenotype vs Genome-Wide Analysis and Correlation

Frontiers in Microbiology, 2020
Klebsiella pneumoniae is one of the leading causes of nosocomial infections. Carbapenem-resistant K. pneumoniae are on the rise globally. The biofilm forming ability of K. pneumoniae further complicates patient management.
N. D. Devanga Ragupathi, D. M. Muthuirulandi Sethuvel, Hariharan Triplicane Dwarakanathan, Dhivya Murugan, Yamini Umashankar, P. Monk, E. Karunakaran, B. Veeraraghavan   +7 more
semanticscholar   +1 more source

High levels of cyclic di-GMP in Klebsiella pneumoniae attenuate virulence in the lung [PDF]

, 2018
The bacterial second messenger bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) has been shown to influence the expression of virulence factors in certain pathogenic bacteria, but little is known about its activity in the increasingly antibiotic-resistant ...
Hunstad, David A, Rosen, David A, Twentyman, Joy   +2 more
core   +2 more sources

Whole-genome sequencing of Klebsiella pneumoniae isolates to track strain progression in a single patient with recurrent urinary tract infection [PDF]

, 2019
Klebsiella pneumoniae is an important uropathogen that increasingly harbors broad-spectrum antibiotic resistance determinants. Evidence suggests that some same-strain recurrences in women with frequent urinary tract infections (UTIs) may emanate from a ...
Minx, Patrick J, Rosen, David A, Wylie, Kristine M, Wylie, Todd N   +3 more
core   +5 more sources

Cell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study

Frontiers in Microbiology, 2022
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance
Xinyi Chen, Jingjing Tian, Can Luo, Xiaofan Wang, Xianping Li, Min Wang   +5 more
doaj   +1 more source

Klebsiella pneumoniae is able to trigger epithelial-mesenchymal transition process in cultured airway epithelial cells [PDF]

, 2016
The ability of some bacterial pathogens to activate Epithelial-Mesenchymal Transition normally is a consequence of the persistence of a local chronic inflammatory response or depends on a direct interaction of the pathogens with the host epithelial cells.
A García-Fernández, A Markogiannakis, A Moustakas, AA Franco, BC Willis, C Passariello, D Kovacs, D Ranieri, Daniela Martinelli, E Candelario-Jalil, Francesca Mazzetta, G Cane, HY Kim, I Pilpilidis, I Santino, Iolanda Santino, J Martinez, JAB Strickertsson, JC Lin, JI Bàrdos, José A. Bengoechea, K Nishi, KK Kim, L Leone, LA Borthwick, Laura Leone, M Barbara, Maurizio Alimandi, ME Falagas, MH Yang, MS Wright, NS Chandel, P Chandrakesan, P Hofman, P Nordmann, R Kalluri, S De Majumdar, S Lamouille, Sabatino Valente, Salvatore Raffa, SS Leonard, SZ Ding, V Cano, Y Kondo, Y Saito, Y Yin, YT Oh   +46 more
core   +2 more sources

Anti-bacterial activity of chitosan loaded plant essential oil against multi drug resistant K. pneumoniae

Saudi Journal of Biological Sciences, 2020
The development of antibiotic resistant in K. pneumoniae is an emerging thread worldwide due to the poor antimicrobial drugs. To overcome this issue, researchers are focused on plant material and their essential oils to fight against multi drug resistant
Feng Zhang, G. Ramachandran, R. Mothana, O. Noman, Waleed A. Alobaid, G. Rajivgandhi, N. Manoharan   +6 more
semanticscholar   +1 more source