Results 81 to 90 of about 24,223,577 (293)

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

open access: yesAdvanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang   +15 more
wiley   +1 more source

Use of the MALDI Biotyper system and the microbiological diagnosis algorithm for identification of non-fermenting bacteria isolated from respiratory tract in cystic fibrosis patients [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2017
The objective of this study was to compare the MALDI Biotyper system and the microbiological diagnosis algorithm for identification of non-fermenting bacteria isolated from respiratory tract in cystic fibrosis patients.
Chernukha M.Yu.   +18 more
doaj  

Evaluate Histological Changes and Resistance to Antibiotics Profile of Bacteria Causing Burn Infection

open access: yesJournal of Pure and Applied Microbiology, 2019
This study analysed Pseudomonas aeruginosa and Staphylococcus aureus burn wound infections, in order to evaluation their incidence, histological change and antimicrobial susceptibilities.
Shawgi A. Elissidig, Samy A. Selim
doaj   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Analysis of susceptibility profile of Pseudomonas spp. and prevalence of bacterial samples from the surfaces of dental consulting-rooms

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2005
The aim of this research was to evaluate the susceptibility profile of Pseudomonas spp. and the prevalence of bacterial samples isolated from horizontal surfaces surrounding wash-basins used by dentists in several adjoined consulting-rooms, at points ...
R.C.L.R. Pietro   +6 more
doaj  

Synthesis and evaluation of polymeric micelle containing piperacillin/tazobactam for enhanced antibacterial activity

open access: yesDrug Delivery, 2019
Infections caused by multidrug-resistant bacteria such as P. aeruginosa are important therapeutic complications. Piperacillin/Tazobactam is considered a safe antimicrobial agent.
Milani Morteza   +4 more
doaj   +1 more source

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

open access: yesAdvanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu   +5 more
wiley   +1 more source

Phagetherapies for infections caused by P. aeruginosa

open access: yes, 2013
The hospital infections can be prevented by controlling some factors related with staff, material, and environment. At this moment the existing legislation regulates procedures that prevent the propagation of the infection and/or of the agents that ...
Prudêncio, Cristina   +5 more
core   +1 more source

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

open access: yesAdvanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song   +9 more
wiley   +1 more source

CRISPRi-Mediated Gene Suppression Reveals Putative Reverse Transcriptase Gene PA0715 to Be a Global Regulator of Pseudomonas aeruginosa

open access: yesInfection and Drug Resistance, 2022
Dapeng Zhou,1,2,* Guangtao Huang,1– 4,* Guangchao Xu,1,2 Lijuan Xiang,5 Siyi Huang,1,2 Xinchong Chen,1,2 Yixin Zhang,4 Dali Wang1,2 1Department of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, People’s ...
Zhou D   +7 more
doaj  

Home - About - Disclaimer - Privacy