Results 211 to 220 of about 52,770 (302)

Lys-specific gingipain (Kgp) of <i>P. gingivalis</i> promotes viral infection by disabling the interferon pathway. [PDF]

mBio
Dobosz E, Golda A, Kanoza M, Kowalczuk W, Potempa B, Potempa J, Gasiorek A, Madeja N, Budziaszek J, Mizgalska D, Yucel-Lindberg T, Koziel J.   +11 more
europepmc   +1 more source

Metagenomic Evaluation of Oral Microbiota in Patients Affected by Oral Lichen Planus: A Pilot Study

Oral Diseases, EarlyView.
ABSTRACT Objective To characterize the oral bacterial and fungal microbiota of symptomatic oral lichen planus patients undergoing topical corticosteroid therapy and to explore microbial patterns potentially associated with subsequent oral candidiasis. Methods Twelve patients with clinically and histologically confirmed OLP were enrolled.
A. Dormiente, L. Mancabelli, M. Ventura, G. Longhi, G. Mergoni, M. Manfredi   +5 more
wiley   +1 more source

Multiomics profiling reveals that P. gingivalis-induced extracellular vesicle reprogramming promotes immune evasion in colorectal cancer through autophagy-mediated STING degradation. [PDF]

Front Cell Infect Microbiol
Zhang X, Huang J, Shang G, Lu Y, Liu H, Zhang Y, Wen F, Xu Y.   +7 more
europepmc   +1 more source

Efficacy of a Hyaluronic Acid‐Based Gel Versus 0.20% Chlorhexidine in Nonsurgical Periodontal Therapy: A Single‐Blind Randomized Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objective To compare the adjunctive efficacy of a hyaluronic acid (HA) gel with 0.20% chlorhexidine (CHX) during nonsurgical periodontal therapy in periodontal patients over 6 months. Methods A single‐blind, randomized, controlled trial included 40 healthy, nonsmoking adults with periodontitis.
Andrea Scribante, Maurizio Pascadopoli, Matteo Pellegrini, Karyna Chekal, Andrea Butera   +4 more
wiley   +1 more source

Biomimetic nanotherapy for <i>P. gingivalis</i>-infected oral squamous cell carcinoma: Photothermal therapy and immunoactivation <i>via</i> precise intracellular bacterial elimination. [PDF]

Int J Pharm X
Dai Z, Li Q, Guo L, Zhong K, Cheng J, Weng X, Cheng B.   +6 more
europepmc   +1 more source

Oral Microbiome Using Colocasia antiquorum var. esculenta Extract Varnish in a Mouse Model with Oral Gavage of P. gingivalis ATCC 53978. [PDF]

Medicina (Kaunas), 2022
Shin SJ, Moon SH, Kim HJ, Oh SH, Bae JM.
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Development of monoclonal antibodies against P. gingivalis Mfa1 and their protective capacity in an experimental periodontitis model. [PDF]

mSphere
Cao M, Wang S, Zhou S, Yan M, Zou Y, Cui Y, Lou X, Gao Y, Chen Y, Han Z, Qian Y, Chen J, Li X.   +12 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles‐Associated DNA Triggers Inflammation by Inducing IL‐6 in Astrocytes

Molecular Oral Microbiology, EarlyView.
Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai, Kaya Yoshida, Yuka Hiroshima, Ayu Ikuta, Mariko Seyama, Yuta Uemura, Hiromichi Yumoto, Kazumi Ozaki   +7 more
wiley   +1 more source