Results 211 to 220 of about 20,775,577 (293)

Identification of a new genetic variant (G231N, E232T, N235D) of peptidylarginine deiminase from <i>P. gingivalis</i> in advanced periodontitis. [PDF]

Front Immunol
Bereta GP, Strzelec K, Łazarz-Bartyzel K, Dziedzic-Kowalska A, Nowakowska Z, Krutyhołowa A, Bielecka E, Kantyka T, Grabiec AM, Kaczmarzyk T, Chomyszyn-Gajewska M, Potempa J, Gawron K.   +12 more
europepmc   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

Periodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje, Ettore Amerio, Irene Mallor, Conrado Aparicio   +3 more
wiley   +1 more source

Genetically engineered M2-like macrophage-derived exosomes for P. gingivalis-suppressed cementum regeneration: From mechanism to therapy. [PDF]

Bioact Mater
Huang X, Deng Y, Xiao J, Wang H, Yang Q, Cao Z.   +5 more
europepmc   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Systemic and local antibiotics in the management of peri‐implantitis: A systematic review and network meta‐analysis

Periodontology 2000, EarlyView.
Abstract Background Peri‐implantitis is a biofilm‐induced inflammatory condition with challenging management due to the complexity of implant surface topographies and the polymicrobial and well‐structured profile of the biofilm colonizing these surfaces.
Jamil A. Shibli, Vittorio Moraschini, Khalila C. Cotrim, Valentim A. R. Barão, Wim Teughels, Thabet Asbi, Daniela F. Bueno, Anton Sculean, João Gabriel S. Souza   +8 more
wiley   +1 more source

Regulated Cell Death In Osteoblast Induced By P. Gingivalis

International Dental Journal
Liao Zekai, Gong Qimei, Tong Zhongchun, Liang Ailin   +3 more
openaire   +1 more source