Results 271 to 280 of about 52,770 (302)

IL-10 Gene Transfer Attenuates P. gingivalis-induced Inflammation

Journal of Dental Research, 2007
IL-10 is an anti-inflammatory cytokine secreted by stimulated Th2 lymphocytes that can down-regulate inflammatory responses to bacterial challenge. We hypothesized that local delivery of IL-10 using gene-transfer will down-regulate inflammatory responses. We examined the effect of IL-10 plasmid injection on the local cytokine response. Two weeks after
Y, Houri-Haddad, W A, Soskolne, A, Halabi, L, Shapira   +3 more
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P. gingivalis antigenic composition

2008
The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ ID NO. 3 or SEQ ID NO.5.
CSL LTD, UNIV MELBOURNE
openaire   +1 more source

Role of Porphyromonas gingivalis 40-kDa outer membrane protein in the aggregation of P. gingivalis vesicles and Actinomyces viscosus

Archives of Oral Biology, 1992
Porphyromonas gingivalis, an important pathogen in periodontitis, produces extracellular vesicles that aggregate with Actinomyces viscosus cells. A 40-kDa outer membrane protein (OMP)-coding gene from P. gingivalis was cloned and the protein was found to be localized in these vesicles.
K, Hiratsuka, Y, Abiko, M, Hayakawa, T, Ito, H, Sasahara, H, Takiguchi   +5 more
openaire   +2 more sources

Distinctive pathways characterize A. actinomycetemcomitans and P. gingivalis.

Molecular biology reports, 2016
The study aimed to compare the molecular mechanism of Porphuromonas gingivalis (P. gingivalis) and Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans). With microarray dataset (GSE9723) from Gene Expression Omnibus, differentially expressed genes (DEGs) were identified comparing normal cell samples with A.
Jing, Lv, Yi-Xin, Zhu, Ying-Qun, Liu, Xin, Xue   +3 more
openaire   +1 more source

Oral immunization with Porphyromonas gingivalis outer membrane protein and CpG oligodeoxynucleotides attenuates P. gingivalis-accelerated atherosclerosis and inflammation

Journal of Oral Biosciences, 2017
Abstract Objective It has previously been shown that oral immunization with the 40-kDa outer membrane protein of Porphyromonas gingivalis (40k-OMP) and CpG oligodeoxynucleotides (ODN) as an adjuvant elicits protective antibody responses against alveolar bone loss caused by P. gingivalis infection.
Takashi Takeuchi, Tomomi Hashizume-Takizawa, Ryoki Kobayashi   +2 more
openaire   +1 more source

P. gingivalis–Induced TLR2 Interactome Analysis Reveals Association with PARP9

Journal of Dental Research
Porphyromonas gingivalis is a Gram-negative anaerobic bacterium strongly associated with periodontal disease. Toll-like receptor 2 (TLR2) is indispensable for the host response to P. gingivalis, but P. gingivalis escapes from immune clearance via TLR2-dependent activation of phosphoinositide-3-kinase (PI3K).
K. Pandi, S. Angabo, H. Makkawi, H. Benyamini, S. Elgavish, G. Nussbaum   +5 more
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[Identification of P. gingivalis P. intermedia P. nigrescens by 16S rDNA and membrane microarray chip].

Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2015
The aim of this study is to identify three kinds of black-pigmented periodontal pathogens P. gingivalis Pg, P. intermedia Pi, P. nigrescens Pn by 16S rDNA and microarray.A pair of universal primers which can amplify a section of conservative domain of bacterial 16S rDNA based on the sequences of 16S rDNA in Genebank were designed.
Zi-sheng, Tang, Hui-min, Cao, Zheng, Liu, Shu-juan, Zhao, Pei, Wang, Jing-ping, Liang, Jian-long, Zhao   +6 more
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Platr3/NUDT21/NF-κB Axis Mediates P. gingivalis-Suppressed Cementoblast Mineralization

Inflammation
Porphyromonas gingivalis (P. gingivalis) is one of the major pathogens causing periodontitis and apical periodontitis (AP). Long noncoding RNA (lncRNA) can regulate cellular mineralization and inflammatory diseases. The aim of this study was to investigate the role and mechanism of lncRNA in P. gingivalis-stimulated cementoblast mineralization. In vivo,
Hantao, Huang, Li, Ma, Xiaoxuan, Wang, Xin, Huang, Huiyi, Wang, Yan, Peng, Junhong, Xiao, Heyu, Liu, Zhengkun, Yang, Zhengguo, Cao   +9 more
openaire   +2 more sources

[Analysis of virulence-related properties of P. gingivalis clinical isolates].

Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2015
To analyze the relation of virulence properties and pathogenicity of Porphyromonas gingivalis (P.gingivals) isolated from Chinese patients.Based on the previous analysis of virulence properties, investigations of pathogenicity properties, including the adhesion to host cells, gingipain activities, and resistance to host immune reaction were performed ...
Yan-bin, Zhou, Da-li, Liu, Yun-peng, Li, Yi-wei, Wang, Rong, Shu   +4 more
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S91. P. Gingivalis and Cardinal Symptoms of Depression

Biological Psychiatry, 2019
Teodor Postolache, Niel Constantine, Melanie Daue, Aline Dagdag, Abhishek Wadhawan, Lisa A. Brenner, Christopher A. Lowry, Hina Makkar, Mark A. Reynolds   +8 more
openaire   +1 more source