Results 261 to 270 of about 52,770 (302)

Theaflavins inhibit pathogenic properties of P. gingivalis and MMPs production in P. gingivalis-stimulated human gingival fibroblasts

Archives of Oral Biology, 2015
Theaflavins, the main polyphenols in black tea, possesses a wide range of beneficial pharmacological properties. Porphyromonas gingivalis (P. gingivalis) is a major aetiological agent associated with periodontitis, a chronic inflammatory disease affecting tooth-supporting tissues. The aim of the present study is to investigate the effect of theaflavins
Lingxue, Kong, Xia, Qi, Shiyan, Huang, Shanshan, Chen, Yafei, Wu, Lei, Zhao   +5 more
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P. gingivalis drives carcinoma progression

Nature Reviews Microbiology, 2020
This study found that the oral pathogen Porphyromonas gingivalis promotes the progression of oesophageal squamous cell carcinoma.
openaire   +2 more sources

Anti-P. gingivalis Response Correlates with Atherosclerosis

Journal of Dental Research, 2007
Significant associations between atherosclerosis and both Porphyromonas gingivalis, a major periodontopathogen, and the respiratory pathogen, Chlamydia pneumoniae, have been shown. Many individuals with evidence of atherosclerosis demonstrate seropositivity to these pathogens.
Ford, Pauline, Gemmell, Edward, Timms, Peter, Chan, A, Preston, F, Seymour, G   +5 more
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Variable Cell Responses to P. gingivalis Lipopolysaccharide

Journal of Dental Research, 2009
Porphyromonas gingivalis is a major etiological agent of chronic periodontal diseases, the virulence of which has been attributed to different factors, including lipopolysaccharide (LPS). We investigated the differential responses induced by P. gingivalis LPS stimulation of human umbilical vein endothelial cells and human oral epithelial cells. RT-PCR
L, Kocgozlu, R, Elkaim, H, Tenenbaum, S, Werner   +3 more
openaire   +2 more sources

Oral infection with P. gingivalis exacerbates autoimmune encephalomyelitis

Journal of Periodontology, 2018
AbstractBackgroundOral infection of mice with P. gingivalis induces periodontal inflammation and attachment loss. The aim of the present study was to investigate whether infection of mice with P. gingivalis, exacerbates the clinical course of experimental autoimmune encephalomyelitis (EAE)—a mouse model of multiple sclerosis (MS).MethodsInduction of ...
David, Polak, Aviv, Shmueli, Talma, Brenner, Lior, Shapira   +3 more
openaire   +2 more sources

Effects of Tobacco and P. gingivalis on Gingival Fibroblasts

Journal of Dental Research, 2010
Cigarette smoke condensate (CSC) is the particulate matter of cigarette smoke. Porphyromonas gingivalis ( P. gingivalis) is an opportunistic pathogen involved in periodontitis. It was hypothesized that the combination of CSC and P. gingivalis would increase the collagen-degrading ability of human gingival fibroblasts (HGFs).
W, Zhang, F, Song, L J, Windsor
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High Antibody Levels to P. gingivalis in Cardiovascular Disease

Journal of Dental Research, 2010
Recent evidence suggests that strain variation in the serum IgG response to Porphyromonas gingivalis occurs in periodontal disease and cardiovascular disease (CVD). This study aimed to test the hypothesis that different P. gingivalis strains would elicit different levels of IgG, depending on a patient’s cardiovascular (CV) and periodontal health.
Bohnstedt, S., Cullinan, M. P., Ford, P. J., Palmer, J. E., Leishman, S. J., Westerman, B., Marshall, R. I., West, M. J., Seymour, G. J.   +8 more
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Dendritic-NK Cell Interactions in P. gingivalis-specific Responses

Journal of Dental Research, 2005
Patients with localized aggressive periodontitis have type-1 cytokines in gingival crevicular fluid and high titers of IFN-γ-dependent IgG2 reactive with P. gingivalis in gingival crevicular fluid and serum. Localized aggressive periodontitis monocytes spontaneously differentiate into dendritic cells that can stimulate IFN-γ production by NK cells ...
T, Kikuchi, D L, Willis, M, Liu, D B, Purkall, S, Sukumar, S E, Barbour, H A, Schenkein, J G, Tew   +7 more
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Interferon-gamma Deficiency Attenuates Local P. gingivalis-induced Inflammation

Journal of Dental Research, 2002
Infection with the periodontal pathogen Porphyromonas gingivalis causes a strong local inflammatory reaction. Using IFNγ-deficient mice, we tested the hypothesis that the absence of IFNγ would result in a reduction of the local pro-inflammatory response to P. gingivalis.
Y, Houri-Haddad, W A, Soskolne, E, Shai, A, Palmon, L, Shapira   +4 more
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Cytokine profiles of Porphyromonas gingivalis‐reactive T lymphocyte lines and clones derived from P. gingivalis‐infected subjects

Oral Diseases, 1995
Porphyromonos gingivolis is generally recognized as a major periodontopathogen such that a study of T cell responses to this organism may help to elucidate immune regulation in periodontal disease.OBJECTIVE The aim of this study was to examine interleukin (IL)‐4, interferon (IFN)‐gamma and IL‐10 production by p‐gingivolis‐responsive T cell lines and ...
Gemmell E., Kjeldsen M., Yamazaki K., Nakajima, Aldred M.J., Seymour   +5 more
openaire   +3 more sources