Results 241 to 250 of about 20,775,577 (293)

Dendritic-NK Cell Interactions in P. gingivalis-specific Responses

Journal of Dental Research, 2005
Patients with localized aggressive periodontitis have type-1 cytokines in gingival crevicular fluid and high titers of IFN-γ-dependent IgG2 reactive with P. gingivalis in gingival crevicular fluid and serum. Localized aggressive periodontitis monocytes spontaneously differentiate into dendritic cells that can stimulate IFN-γ production by NK cells ...
T. Kikuchi, D. Willis, M. Liu, D. Purkall, S. Sukumar, S. Barbour, H. Schenkein, J. Tew   +7 more
semanticscholar   +3 more sources

Isoliquiritigenin alleviates P. gingivalis-LPS/ATP-induced pyroptosis by inhibiting NF-κB/ NLRP3/GSDMD signals in human gingival fibroblasts.

International Immunopharmacology, 2021
OBJECTIVE To investigate whether pyroptosis is induced by Porphyromonas gingivalis-lipopolysaccharide (P. gingivalis-LPS)/ adenosine triphosphate (ATP) through NF-κB/NLRP3/GSDMD signaling in human gingival fibroblasts (HGFs) and whether isoliquiritigenin
Xiaofang Lv, Chun Fan, Zhongxin Jiang, Wenxuan Wang, Xu Qiu, Q. Ji   +5 more
semanticscholar   +1 more source

High molecular weight hyaluronic acid regulates P. gingivalis-induced inflammation and migration in human gingival fibroblasts via MAPK and NF-κB signaling pathway.

Archives of Oral Biology, 2019
Chronic periodontitis is associated with Porphyromonas gingivalis (P. gingivalis) infection. Hyaluronic Acid (HA), a critical component of the extracellular matrix, exhibits anti-inflammatory and wound-healing properties.
Minshan Chen, Lin Li, Zhenshi Wang, Ping Li, Feng Feng, Xi Zheng   +5 more
semanticscholar   +1 more source

[Effect of A.viscosus on growth of P. gingivalis in vitro].

Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2015
To investigate the effect of A. viscosus on growth of P. gingivalis in vitro.Groups as single-species(A.viscosus or P.gingivalis) and dual-species (A.viscosus and P.gingivalis) were incubated in BHI broth anaerobically at 37 degrees C, and growth curve of each group was monitored for 48 hours; Meanwhile the dual-species cultures of 2-hour interval were
Yan, Miao, Miao, Yu, Yao-lun, Han, Yu-qing, Hao   +3 more
openaire   +2 more sources

The involvement of Kav001 in inhibition of LPS/P. gingivalis‐induced

Journal of Cellular Biochemistry, 2018
AbstractTNF‐a is an important cytokine mediator of inflammation which suggests that inhibition of TNF activity may provide potential for clinical application. Recent data indicated that treatment of both human and mouse cells with Kavain significantly modulates P. gingivalis‐ and LPS‐induced TNF‐α expression.
Xiaoren Tang, Mansour Alasiri, Abdullah Bamashmous, Bushra Aljahdali, Feng Cao, Serge Dibart, Erdjan Salih   +6 more
openaire   +2 more sources

Oral infection with P. gingivalis exacerbates autoimmune encephalomyelitis

Journal of Periodontology, 2018
AbstractBackgroundOral infection of mice with P. gingivalis induces periodontal inflammation and attachment loss. The aim of the present study was to investigate whether infection of mice with P. gingivalis, exacerbates the clinical course of experimental autoimmune encephalomyelitis (EAE)—a mouse model of multiple sclerosis (MS).MethodsInduction of ...
David, Polak, Aviv, Shmueli, Talma, Brenner, Lior, Shapira   +3 more
openaire   +2 more sources

Ckip-1 Mediates P. gingivalis –Suppressed Cementoblast Mineralization

Journal of Dental Research, 2021
Porphyromonas gingivalis is responsible for the destruction of cementum in patients with periodontitis and periapical periodontitis. However, research about the effects of P. gingivalis on cementoblast mineralization and the underlying mechanism is still lacking.
X. Huang, L. Ma, X. Wang, H. Wang, Y. Peng, X. Gao, H. Huang, Y. Chen, Y. Zhang, Z. Cao   +9 more
openaire   +2 more sources

Porphyromonas gingivalis fimbriae are pro-inflammatory but do not play a prominent role in the innate immune response to P. gingivalis

Journal of Endotoxin Research, 2005
The fimA gene encodes the major fimbrial protein of Porphyromonas gingivalis. It has been shown to stimulate adhesion to salivary proteins and other bacteria. It is also thought to play a major role in invading and stimulating host cells. To determine whether the fimA gene represents one of the principal molecules of P.
Dana T, Graves, Ghada, Naguib, Huafei, Lu, Tesfahun, Desta, Salomon, Amar   +4 more
openaire   +2 more sources

Distinctive pathways characterize A. actinomycetemcomitans and P. gingivalis.

Molecular biology reports, 2016
The study aimed to compare the molecular mechanism of Porphuromonas gingivalis (P. gingivalis) and Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans). With microarray dataset (GSE9723) from Gene Expression Omnibus, differentially expressed genes (DEGs) were identified comparing normal cell samples with A.
Jing, Lv, Yi-Xin, Zhu, Ying-Qun, Liu, Xin, Xue   +3 more
openaire   +1 more source

[The impact of S.gordonii on P. gingivalis on the form of biofilm].

Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2016
To investigate the impact of S.gordonii on the ultrastructure of P. gingivalis biofilm and on the amount of P. gingivalis in biofilm.P. gingivalis and/or S.gordonii grew on the culture slides to form single P. gingivalis biofilm and heterotypic biofilm of P.gingivalis-S.gordonii.
Dong-mei, Zhang, Jing-bo, Liu, Ya-ping, Pan, Jia-yu, Pan, Qiu-fang, Xu   +4 more
openaire   +1 more source