Results 51 to 60 of about 24,104,894 (214)

Limited polymorphism of the Kelch propeller domain in Plasmodium malariae and P. ovale isolates from Thailand [PDF]

, 2016
Artemisinin resistance in Plasmodium falciparum, the agent of severe malaria, is currently a major obstacle to malaria control in Southeast Asia. A gene named “kelch13” has been associated with artemisinin resistance in P. falciparum.
Pukrittayakamee, SasithonNicholas, Dondorp, AM, Dondorp, A, Saralamba, Naowarat, Dondorp, Adrianus, Nakeesathit, Supatchara, Saralamba, N, Imwong, Mallika, Dondorp, Arjen, White, Nicholas J, Pukrittayakamee, S, Imwong, M, Nosten, Francois, White, NJ, White, Nicholas, Nosten, F, Nakeesathit, S   +16 more
core   +1 more source

Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae. [PDF]

, 2008
Plasmodium falciparum and P. malariae occur endemically in many parts of Africa. Observations from malariotherapy patients suggest that co-infection with P. malariae may increase P. falciparum gametocyte production. We determined P. falciparum gametocyte
Sauerwein, Robert W, Drakeley, Chris J, Bousema, J. Teun, Bousema, J Teun, Bousema, J.T., Sauerwein, R.W., Drakeley, Chris J., Omar, Sabah A, Schallig, Henk, Mens, Petra F, Houben, Rein, Omar, S.A., Houben, R., Mens, Petra F., Drakeley, C., Mens, P.F., Gouagna, Louis C., Arens, Theo, Omar, Sabah A., Schallig, H., Sauerwein, Robert W., Arens, T., Gouagna, Louis C, Gouagna, L.C.   +23 more
core   +2 more sources

Genetic diversity of Plasmodium malariae in sub-Saharan Africa: a two-marker genotyping approach for molecular epidemiological studies

Frontiers in Cellular and Infection Microbiology
IntroductionPlasmodium malariae is the most common non-falciparum species in sub-Saharan Africa. Despite this, data on its genetic diversity is scarce. Therefore, we aimed to establish a P.
Miriam Rodi, Katarzyna Kawecka, Laura Stephan, Lilith Berner, Martha Salinas Medina, Albert Lalremruata, Albert Lalremruata, Tamirat Gebru Woldearegai, Tamirat Gebru Woldearegai, Pierre Blaise Matsiegui, Mirjam Groger, Mirjam Groger, Rella Zoleko Manego, Rella Zoleko Manego, Rella Zoleko Manego, Dorothea Ekoka Mbassi, Dorothea Ekoka Mbassi, Dorothea Ekoka Mbassi, Ghyslain Mombo-Ngoma, Ghyslain Mombo-Ngoma, Ghyslain Mombo-Ngoma, Selidji Todagbe Agnandji, Selidji Todagbe Agnandji, Michael Ramharter, Michael Ramharter, Michael Ramharter, Benjamin Mordmüller, Benjamin Mordmüller, Benjamin Mordmüller, Juliana Inoue, Jana Held, Jana Held, Jana Held   +32 more
doaj   +1 more source

Epidemiologic aspects of the malaria transmission cycle in an area of very low incidence in Brazil

Malaria Journal, 2007
Background Extra-Amazonian autochthonous Plasmodium vivax infections have been reported in mountainous regions surrounded by the Atlantic Forest in Espírito Santo state, Brazil.
Rezende Helder R, Falqueto Aloísio, Hatab Maria do Carmo LD, Coutinho Arnídio F, Boulos Marcos, Cerutti Crispim, Duarte Ana Maria RC, Collins William, Malafronte Rosely S   +8 more
doaj   +1 more source

Genetic diversity of three surface protein genes in Plasmodium malariae from three Asian countries

Malaria Journal, 2018
Background Genetic diversity of the three important antigenic proteins, namely thrombospondin-related anonymous protein (TRAP), apical membrane antigen 1 (AMA1), and 6-cysteine protein (P48/45), all of which are found in various developmental stages of ...
Suttipat Srisutham, Naowarat Saralamba, Kanlaya Sriprawat, Mayfong Mayxay, Frank Smithuis, Francois Nosten, Sasithon Pukrittayakamee, Nicholas P. J. Day, Arjen M. Dondorp, Mallika Imwong   +9 more
doaj   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Donor management implications for high‐sensitivity detection of low‐level malaria parasitemia in blood donor screening

Transfusion, EarlyView.
Abstract Introduction Transfusion‐transmitted malaria can occur when donors have unrecognized asymptomatic infection with submicroscopic parasitemia, highlighting the need to detect low‐level parasitemia in blood donor screening. However, these highly sensitive blood donor testing algorithms may refer donors to clinicians who use diagnostic algorithms ...
Carmen L. Charlton, Valerie Conrod, Dilini Kumaran, Craig Jenkins, Sandy Shokoples, LeeAnn Turnbull, Ruwandi Kariyawasam, Chantale Pambrun, Steven J. Drews   +8 more
wiley   +1 more source

Identification and typing of Cameroonian isolates of P-malariae using monoclonal antibodies against P-brasilianum

, 2006
In the present study, monoclonal antibodies raised against Plasmodium brasilianum were used to demonstrate, for the first time, antigenic diversity in natural populations of Plasmodium malariae isolates and as diagnostic tool to detect low parasitaemia P.
Zakeri, S., Lindergard, G., Boudin, C., Davies, R. M., Hommel, Marcel, Louis, F.   +5 more
core   +1 more source

Unresolved direction of host transfer of Plasmodium vivax v. P. simium and P. malariae v. P. brasilianum [PDF]

, 2011
The evolutionary history of two human malaria parasites, Plasmodium vivax and Plasmodium malariae, remains unresolved. The near genetic identity between human P. vivax and P. malariae, and primate P. simium and P. brasilianum, respectively, suggests that
Tazi, Loubna, Ayala, Francisco J, Francisco J. Ayala, Loubna Tazi   +3 more
core   +1 more source

Budget impact of implementing universal Plasmodium NAT screening in the blood transfusion system in the US

Transfusion, EarlyView.
Abstract Background Blood donor deferral for malaria risk relies exclusively on responses to self‐reported questionnaires. This study evaluated the economic impact of introducing Plasmodium nucleic acid testing (NAT) as a universal screening strategy in the United States.
Cristina Coll‐Ortega, Elisabet Viayna, Jiani Zhou, Susan L. Stramer   +3 more
wiley   +1 more source