Results 81 to 90 of about 24,104,894 (214)

Small Molecule Kinase Inhibitors with In Vitro β‐Hematin Formation and Plasmodium falciparum Protein Kinase G Inhibitory Activity Identified Using Machine Learning

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
A random forest machine learning model was used in combination with molecular docking to predict activity of small molecule kinase inhibitors against two crucial antimalarial targets, namely hemozoin crystallization and Plasmodium falciparum protein kinase G. Derazantinib shows most promise as a dual inhibitor.
Jessica L. Thibaud, Nicolaas Salomane, Sarah Harries, Kathryn J. Wicht, Lauren B. Coulson, David Kuter, Kelly Chibale, Katherine A. de Villiers   +7 more
wiley   +1 more source

Replication Data for: Identification of two genomic cryptotypes of Plasmodium malariae in Africa

These data and scripts are accompanying the manuscript: "Identification of two genomic cryptotypes of Plasmodium malariae in Africa" by Margaux J. M. Lefebvre*, Céline Arnathau, Sandrine Houzé, Benoit de Thoisy, Camila González, Silvia Rondón, Arnab Pain,
Lefebvre, Margaux, Rondón, Silvia, Pain, Arnab, Arnathau, Céline, Fontaine, Michael C., González, Camila, Rougeron, Virginie, De Thoisy, Benoit, Houzé, Sandrine, Prugnolle, Franck   +9 more
core   +1 more source

ama1 genes of sympatric Plasmodium vivax and P. falciparum from Venezuela differ significantly in genetic diversity and recombination frequency. [PDF]

, 2008
BACKGROUND: We present the first population genetic analysis of homologous loci from two sympatric human malaria parasite populations sharing the same human hosts, using full-length sequences of ama1 genes from Plasmodium vivax and P.
Sutherland, Colin J, Rosalynn L Ord, Adriana Tami, Tami, Adriana, Colin J Sutherland, Ord, Rosalynn L, Tami, Adriana; id_orcid   +6 more
core   +3 more sources

Malian field isolates provide insight into Plasmodium malariae intra-erythrocytic development and invasion.

PLoS Neglected Tropical Diseases
Plasmodium malariae is the third most prevalent human malaria parasite species and contributes significantly to morbidity. Nevertheless, our comprehension of this parasite's biology remains limited, primarily due to its frequent co-infections with other ...
Francois Dao, Amadou Niangaly, Fanta Sogore, Mamadou Wague, Djeneba Dabitao, Siaka Goita, Aboubacrin S Hadara, Ousmaila Diakite, Mohamed Maiga, Fatoumata O Maiga, Chantal Cazevieille, Cecile Cassan, Arthur M Talman, Abdoulaye A Djimde, Alejandro Marin-Menendez, Laurent Dembélé   +15 more
doaj   +1 more source

Molecular Detection of Plasmodium malariae/Plasmodium brasilianum in Non-Human Primates in Captivity in Costa Rica.

PLoS ONE, 2017
One hundred and fifty-two blood samples of non-human primates of thirteen rescue centers in Costa Rica were analyzed to determine the presence of species of Plasmodium using thick blood smears, semi-nested multiplex polymerase chain reaction (SnM-PCR ...
Alicia Fuentes-Ramírez, Mauricio Jiménez-Soto, Ruth Castro, Juan José Romero-Zuñiga, Gaby Dolz   +4 more
doaj   +1 more source

Asymptomatic Plasmodium Infections in Children in Low Malaria Transmission Setting, Southwestern Uganda

Emerging Infectious Diseases, 2016
A survey of asymptomatic children in Uganda showed Plasmodium malariae and P. falciparum parasites in 45% and 55% of microscopy-positive samples, respectively. Although 36% of microscopy-positive samples were negative by rapid diagnostic test, 75% showed
Michelle E. Roh, Caesar Oyet, Patrick Orikiriza, Martina Wade, Gertrude N. Kiwanuka, Juliet Mwanga-Amumpaire, Sunil Parikh, Yap Boum   +7 more
doaj   +1 more source

Trends of neglected Plasmodium species infection in humans over the past century in India

One Health, 2020
Background: Efforts for malaria elimination in India focus solely on the more prevalent human malaria parasites of Plasmodium falciparum (Pf) and Plasmodium vivax (Pv).
Rini Chaturvedi, Nimita Deora, Deepam Bhandari, Suhel Parvez, Abhinav Sinha, Amit Sharma   +5 more
doaj   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Re-emergence of Plasmodium malariae in Costa Rica

, 2015
In this paper we report the diagnosis of four cases of Plasmodium malariae in humans in Costa Rica, using parasitological and molecular techniques. Real-time PCR detected P.
Dolz, Gaby, Solórzano-Morales, Antony, Herrero-Acosta, Marco Vinicio, Morera, Jessica, Calvo, Nidia   +4 more
core   +1 more source

Heritability of P. falciparum and P. vivax Malaria in a Karen Population in Thailand

PLoS ONE, 2008
ركزت غالبية الدراسات المتعلقة بعلم الوراثة المضيفة للملاريا على الجينات الفردية التي تمنح الحماية ضد الملاريا بدلاً من التعرض لها. إن تحديد التأثير النسبي للعوامل الوراثية مقابل العوامل غير الوراثية على عدوى الملاريا ومرضها أمر ضروري لتركيز الجهود على العوامل المحددة الرئيسية.
Waraphon Phimpraphi, Paul Rácz, Bhee Witoonpanich, Chairat Turbpaiboon, Chayanon Peerapittayamongkol, Chalisa Louicharoen, Isabelle Casadémont, Sumalee Tungpradabkul, Srivicha Krudsood, Jaranit Kaewkunwal, Thanyachai Sura, Sornchai Looareesuwan, Pratap Singhasivanon, Anavaj Sakuntabhai   +13 more
openaire   +5 more sources