Results 81 to 90 of about 870,001 (220)
Plasma Proteome Profiling of Centenarian Across Switzerland Reveals Key Youth‐Associated Proteins
We characterized the plasma proteomic profiles of centenarians from the SWISS100 cohort, identifying 583 differentially expressed proteins compared to younger and geriatric groups. Cross‐validation with the independent datasets NECS and the TAME consortium confirmed a robust aging signature, while fractional polynomial regressions revealed a specific ...
Flavien Delhaes +8 more
wiley +1 more source
Profound Cognitive Impairment as a Salient Feature of Multiple Sclerosis: A Case Report
ABSTRACT Background Cognitive impairment affects up to two‐thirds of patients with multiple sclerosis (MS); however, profound global deficits, defined as a full‐scale IQ below 70, are uncommon and rarely constitute the primary symptom. Case Presentation We describe a 27‐year‐old woman with severe multidomain cognitive impairment due to MS ...
Shota Ito +3 more
wiley +1 more source
Significance of retinal structural and functional damage in diagnosis of Alzheimer's disease
Objective To assess the value of detecting retinal changes with pattern visual evoked potential (PVEP) combined with optical coherence tomography (OCT) in the diagnosis of Alzheimer's disease (AD).
WU Hanyun +5 more
doaj +1 more source
Visual activation of auditory cortex reflects maladaptive plasticity in cochlear implant users [PDF]
Cross-modal reorganization in the auditory cortex has been reported in deaf individuals. However, it is not well understood whether this compensatory reorganization induced by auditory deprivation recedes once the sensation of hearing is partially ...
Debener, Stefan +8 more
core
ABSTRACT Auditory hypersensitivity is a prominent symptom in Fragile X syndrome (FXS), the most prevalent monogenic cause of autism and intellectual disability. FXS arises through the loss of the protein encoded by the FMR1 (Fragile X Messenger Ribonucleoprotein 1) gene, FMRP, required for normal neural circuit excitability.
Dorit Möhrle +4 more
wiley +1 more source
Purpose:- To investigate the visual evoked potentials in Type II diabetic patients in order to determine the alterations, if any, resulting from visual impairment due to diabetes mellitus (DM).
Ruchi Kothari +3 more
doaj +1 more source
We propose a lightweight deep‐learning framework for efficient retinal disease diagnosis using optical coherence tomography images, combining lite convolution and global‐local fusion blocks for enhanced feature extraction. Achieving up to 99.70% accuracy on benchmark datasets with only 0.27M parameters, the model ensures high performance, low ...
Utsab Saha +3 more
wiley +1 more source
Implementing implicit OpenMP data sharing on GPUs
OpenMP is a shared memory programming model which supports the offloading of target regions to accelerators such as NVIDIA GPUs. The implementation in Clang/LLVM aims to deliver a generic GPU compilation toolchain that supports both the native CUDA C/C++
Bataev, Alexey +8 more
core +1 more source
Tailored modifications to the classification head and fine‐tuning strategies to improve model robustness and performance. A comprehensive comparative study leveraging transfer learning techniques for multi‐class eye disease classification, evaluating efficacy in diagnosing cataract, diabetic retinopathy and glaucoma.
Souhardo Rahman +4 more
wiley +1 more source
ABSTRACT While substantial individual differences in face processing abilities are well established, their neural basis remains underexplored. Moreover, while recent years have seen an increased interest in highly powered replications of event‐related potential (ERP) studies, experiments estimating ERP face processing effects with high precision are ...
Maria Ciocan +4 more
wiley +1 more source

