Results 21 to 30 of about 57,796 (112)

miR-410 induces both epithelial–mesenchymal transition and radioresistance through activation of the PI3K/mTOR pathway in non-small cell lung cancer

Signal Transduction and Targeted Therapy, 2020
Radiotherapy remains one of the major treatments for non-small cell lung cancer (NSCLC) patients; whereas intrinsic or acquired radioresistance limits its efficacy. Nevertheless, most studies so far have only focused on acquired resistance.
Yue Yuan, H. Liao, Q. Pu, Xixian Ke, Xueting Hu, Yongfang Ma, Xinmei Luo, Q. Jiang, Y. Gong, Min Wu, Lunxu Liu, Wen Zhu   +11 more
semanticscholar   +1 more source

miR-410-3P inhibits adipocyte differentiation by targeting IRS-1 in cancer-associated cachexia patients

Lipids in Health and Disease, 2021
Cancer-associated cachexia (CAC) is a metabolic syndrome characterized by progressive depletion of adipose and muscle tissue that cannot be corrected by conventional nutritional therapy.
Diya Sun, Zuoyou Ding, Lei Shen, Fan Yang, Jun Han, Guohao Wu   +5 more
semanticscholar   +1 more source

11th Asian Conference on Emergency Medicine (ACEM) 2021 Conference proceedings

, 2022
Hong Kong Journal of Emergency Medicine, Volume 29, Issue S1, Page 2S-87S, June 2022.
wiley   +1 more source

Gβγ is a direct regulator of endogenous p101/p110γ and p84/p110γ PI3Kγ complexes in mouse neutrophils

Science Signaling, 2020
PI3Kγ complexes containing p101 or p84 are directly activated by Gβγ in a GPCR-dependent manner in neutrophils. How to activate PI3Kγ in neutrophils A critical effector of GPCRs in neutrophils is PI3Kγ, but how the two PI3Kγ complexes are activated by ...
Natalie K. Rynkiewicz, K. Anderson, S. Suire, Daniel M. Collins, Eleftherios Karanasios, O. Vadas, Roger L. Williams, David Oxley, J. Clark, L. Stephens, P. Hawkins   +10 more
semanticscholar   +1 more source

LncRNA NEAT1 Targets Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via the miR-410-3p/YY1 Axis

Frontiers in Immunology, 2020
LncRNA NEAT1 functions as an oncogene in multiple human cancers. However, its expression and role in fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA) remain unclear.
Yuejiao Wang, Lin-xin Hou, Xiaowei Yuan, Neili Xu, Shuai Zhao, Li-li Yang, Ning Zhang   +6 more
semanticscholar   +1 more source

Three Women, Three Generations: An In-Depth Case Study of Language Retention and Shift in One Family from the Maltese Australian Community in Melbourne [PDF]

This paper analysis one family pertaining to the Maltese Australian community in Melbourne and investigates the retention of the Maltese language The Maltese Australian community is a small community that is getting smaller since migration from Malta to
Adrian Muscat
core   +2 more sources

Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway

Journal of Translational Medicine
Background Macrophages phenotypic deviation and immune imbalance play vital roles in pregnancy-associated diseases such as spontaneous miscarriage.
Jing Yang, Longfei Li, Linlin Wang, Ruizhi Chen, Xiaobing Yang, Juanhua Wu, Gang Feng, Jinli Ding, Lianghui Diao, Jiao Chen, Jing Yang   +10 more
semanticscholar   +1 more source

MicroRNA-410-3p modulates chondrocyte apoptosis and inflammation by targeting high mobility group box 1 (HMGB1) in an osteoarthritis mouse model

BMC Musculoskeletal Disorders, 2020
Background Osteoarthritis (OA) is the most prevalent type of arthritis, which commonly involves inflammation in the articular cartilage in OA pathogenesis.
H. Pan, Huming Dai, Linzhi Wang, Silong Lin, Yuefeng Tao, Yi Zheng, Renyi Jiang, F. Fang, Yifan Wu   +8 more
semanticscholar   +1 more source

Exosomes Derived from Hypoxic Colorectal Cancer Cells Transfer miR-410-3p to Regulate Tumor Progression

Journal of Cancer, 2020
Hypoxia is a common characteristic of solid tumors and is associated with cancer progression and poor outcomes. However, the roles and specific mechanisms of exosomes and hypoxia during cancer progression still remain unclear.
Xiu-feng Hu, Y. Mu, Jie Liu, X. Mu, Fangfang Gao, Li-juan Chen, Hui-juan Wu, Hong-bo Wu, Wenjing Liu, Yanqiu Zhao   +9 more
semanticscholar   +1 more source

Mitigating Scatter in Mechanical Properties in AISI 410 Fabricated via Arc-Based Additive Manufacturing Process

Materials, 2020
Wire-based metal additive manufacturing utilizes the ability of additive manufacturing to fabricate complex geometries with high deposition rates (above 7 kg/h), thus finding applications in the fabrication of large-scale components, such as stamping ...
Sougata Roy, Benjamin Shassere, Jake K. Yoder, A. Nycz, M. Noakes, B. Narayanan, L. Meyer, J. Paul, N. Sridharan   +8 more
semanticscholar   +1 more source