Results 261 to 270 of about 481,863 (320)

Targeting cellular senescence in progenitor cells as a strategy to enhance bone regeneration by cell therapies: a systematic review of pre-clinical investigations. [PDF]

Stem Cell Res Ther
Morita M, Damle EB, Shinohara I, Murayama M, Susuki Y, Gao Q, Ma C, Chow SK, Goodman SB.   +8 more
europepmc   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

P21-positive senescent stromal cells promote prostate cancer immune suppression and progression that can be reversed by senolytic therapy. [PDF]

Cancer Discov
Zhou L, DeMarco KD, Murphy KC, Wu Z, Li J, Johnson C, Liu B, Giwa HK, Ma B, Bhalerao N, Li J, Jiang Z, Bai S, Parikh CN, Ye T, Simin K, Zhu LJ, Pitarresi JR, Wu H, Ruscetti M.   +19 more
europepmc   +1 more source

Atmosphere‐Regulated Pyrolysis Switches ORR Pathway on Iron‐Based Catalyst for H2O2 Synthesis and Zn‐Air Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Two Fe‐based electrocatalysts with different ORR selectivity were synthesized from a FeMOF in N2 or air atmosphere, which show promising prospects in Zn‐air battery and H2O2 production. Developing simple methods to achieve flexible regulation of oxygen reduction reaction (ORR) selectivity is essential for sustainable energy technologies, yet remains ...
Songhan Hu, Mingyuan Ma, Xinxin Xu, Kai Wang, Qiang Wang   +4 more
wiley   +1 more source

Triclosan exacerbates post-myocardial infarction injury via Nur77 ubiquitination: Linking NTRK2/PGC-1α-mediated mitochondrial dysfunction to senescence and ferroptosis. [PDF]

Redox Biol
Yang B, Chen Y, Zheng X, Li T, Niu K, Wang Z, Xu X, Huang Q, Wang X, Fang Y, Liu W, Yu Z, Wei D, Zhu Y, Jin X, Shen C.   +15 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

A new SO₂ probe ZSO targeting VDBP inhibits high glucose induced endothelial cell senescence and calcification. [PDF]

Front Physiol
Zhang Y, Yan X, Dong X, Zhao C, Chi X, Zhao B, Miao J, Lin Z.   +7 more
europepmc   +1 more source

Synthesis and Investigation of Bonding Scenario in a Bis(silaselenone)

European Journal of Inorganic Chemistry, EarlyView.
Silaselenones, the compounds containing Si=Se bond, are rarely reported in the literature. Silaselenones are the class of compounds that possess Si=Se bond. Herein, we report a bis(silaselenone) and we investigate nature of bonding between Si–Si atoms and Si—Amidinate moieties by employing Natural bond orbital (NBO), Quantum theory of atoms in ...
Saroj Kumar Kushvaha, Harsha S. Karnamkkott, Paula A. M. Stark, Sai Manoj N. V. T. Gorantla, Regine Herbst‐Irmer, Kartik Chandra Mondal, Dietmar Stalke, Herbert W. Roesky   +7 more
wiley   +1 more source