Results 281 to 290 of about 481,863 (320)
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Ras p21: effects and regulation
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1991III. Factors controlling GDP/GTP exchange . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218 A. Exchange factors in mammals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218 B. Exchange factor in yeast . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
H, Haubruck, F, McCormick
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p21-Activated Kinase Inhibitors
2013The p21-activated kinases (PAKs) are Ser/Thr kinases in the STE20 kinase family with important roles in regulating cytoskeletal organization, cell migration, and signaling. The PAK enzyme family comprises six members subdivided into two groups: Group I, represented by PAK1, 2, and 3, and Group II, represented by PAK 4, 5, and 6, based on sequence and ...
Joachim, Rudolph +3 more
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p21-activated kinases in cancer
Nature Reviews Cancer, 2006The pivotal role of kinases in signal transduction and cellular regulation has lent them considerable appeal as pharmacological targets across a broad spectrum of cancers. p21-activated kinases (Paks) are serine/threonine kinases that function as downstream nodes for various oncogenic signalling pathways.
Rakesh, Kumar +2 more
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Sotos syndrome and de novo balanced autosomal translocation (t(3;6)(p21;p21))
Clinical Genetics, 1990In this report we describe a 6‐year‐old boy with Sotos syndrome and a de novo apparently balanced 3/6 translocation (karyotype: 46,XY,t(3;6)(p21;p21)). Pre‐ and postnatal overgrowth are observed in an increasing number of conditions of variable etiology.
C T, Schrander-Stumpel +2 more
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Crystallography Reports, 2003
A systematic investigation into the general structural features of centric and acentric polymorphic pairs of organic molecular crystals is performed using the data available in the Cambridge Structural Database. The structural aspects of the P21/c-P21, P21/c-Pc, and P21/c-Pna21 polymorphic pairs are considered.
L. N. Kuleshova, M. Yu. Antipin
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A systematic investigation into the general structural features of centric and acentric polymorphic pairs of organic molecular crystals is performed using the data available in the Cambridge Structural Database. The structural aspects of the P21/c-P21, P21/c-Pc, and P21/c-Pna21 polymorphic pairs are considered.
L. N. Kuleshova, M. Yu. Antipin
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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
Cell, 1993J. Harper +4 more
semanticscholar +1 more source
p21 is a universal inhibitor of cyclin kinases
Nature, 1993Y. Xiong +5 more
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Requirement for p53 and p21 to sustain G2 arrest after DNA damage.
Science, 1998F. Bunz +8 more
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