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P2X Receptors and Diabetes

Current Medicinal Chemistry, 2015
Diabetes is a metabolic disorder characterized by elevation of glucose levels in the blood that develops in humans as a result of genetic predisposition and environmental factors. Unbalanced glycemic control has been associated with the development of progressive and debilitating complications that dramatically affect the quality of life and life ...
C. Fotino   +3 more
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Biophysics of P2X receptors

Pflügers Archiv - European Journal of Physiology, 2006
The P2X receptor is the baby brother of the ligand-gated ion channel super-family. An understanding of its role in human physiology is still developing, and no one truly knows how it works to transport ions across the membrane. In this study, we review some aspects of P2X channel biophysics, concentrating on ion permeation and gating.
Zhiyuan Li   +2 more
openaire   +2 more sources

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