Results 131 to 140 of about 2,327,568 (312)

INVESTIGATION INTO P2Y RECEPTOR FUNCTION IN PLATELETS FROM PATIENTS WITH SEPSIS. [PDF]

Shock, 2023
Arkless KL, Fish M, Jennings A, Page CP, Shankar-Hari M, Pitchford SC.   +5 more
europepmc   +1 more source

Purinergic mechanisms in neuroinflammation: An update from molecules to behavior. [PDF]

, 2015
The principle functions of neuroinflammation are to limit tissue damage and promote tissue repair in response to pathogens or injury. While neuroinflammation has utility, pathophysiological inflammatory responses, to some extent, underlie almost all ...
Beamer, Edward, Bekő, Katinka, Gölöncsér, Flóra, Horváth, Gergely, Koványi, Bence, Otrokocsi, Lilla, Sperlágh, Beáta   +6 more
core   +1 more source

Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages. [PDF]

EMBO J, 2023
Andersen LL, Huang Y, Urban C, Oubraham L, Winheim E, Stafford C, Nagl D, O'Duill F, Ebert T, Engleitner T, Paludan SR, Krug A, Rad R, Hornung V, Pichlmair A.   +14 more
europepmc   +1 more source

Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease

BMC Medical Genetics, 2007
Background The platelet P2Y12 receptor plays a key role in platelet activation. The H2 haplotype of the P2Y12 receptor gene (P2RY12) has been found to be associated with maximal aggregation response to adenosine diphosphate (ADP) and with increased risk ...
Martinelli Nicola, Olivieri Oliviero, Girelli Domenico, Biscuola Michele, Malerba Giovanni, Trabetti Elisabetta, Cavallari Ugo, Angiolillo Dominick J, Corrocher Roberto, Pignatti Pier   +9 more
doaj   +1 more source

Characterisation of P2Y receptor subtypes mediating vasodilation and vasoconstriction of rat pulmonary artery using selective antagonists. [PDF]

Purinergic Signal, 2022
Dales MO, Mitchell C, Gurney AM, Drummond RM, Kennedy C.   +4 more
europepmc   +1 more source

Selective permeabilization of cervical cancer cells to an ionic DNA‐binding cytotoxin by activation of P2Y receptors [PDF]

, 2015
Maurish Bukhari, Han Deng, Noelle Jones, Zachary Towne, Craig D. Woodworth, Damien S. K. Samways   +5 more
openalex   +1 more source

The role of P2Y₂ nucleotide receptors in vascular inflammation [PDF]

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf ...
Yu, Ningpu, 1979-
core   +1 more source

Prostaglandin E2 Impairs P2Y2/P2Y4 Receptor Signaling in Cerebellar Astrocytes via EP3 Receptors

Frontiers in Pharmacology, 2017
Prostaglandin E2 (PGE2) is an important bioactive lipid that accumulates after tissue damage or inflammation due to the rapid expression of cyclooxygenase 2. PGE2 activates specific G-protein coupled EP receptors and it mediates pro- or anti-inflammatory
Lucía Paniagua-Herranz, Juan C. Gil-Redondo, Ma José Queipo, Silvia González-Ramos, Lisardo Boscá, Raquel Pérez-Sen, Ma Teresa Miras-Portugal, Esmerilda G. Delicado   +7 more
doaj   +1 more source

2‐Chloro N⁶‐methyl‐(N)‐methanocarba‐2′‐deoxyadenosine‐3′,5′‐bisphosphate is a selective high affinity P2Y₁ receptor antagonist [PDF]

, 2002
José L. Boyer, Mary Adams, R. Gnana Ravi, Kenneth A. Jacobson, T. Kendall Harden   +4 more
openalex   +1 more source

P₂X and P2Y receptor antagonists reduce inflammation in ATP-induced microglia. [PDF]

Pharm Pract (Granada), 2023
Imraish A, Abu-Thiab T, Hammad H.
europepmc   +1 more source