Results 141 to 150 of about 71,455 (301)
Spontaneous regression of equine sarcoids is an exceptional event
Equine Veterinary Journal, Volume 58, Issue 4, Page 889-894, July 2026.Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley +1 more source
Performance of cognitive tasks and functional brain activity in anxiety disorders
Обозрение психиатрии и медицинской психологии имени В.М. БехтереваObjective. To improve understanding of psychophysiological underpinnings of anxiety disorders a comprehensive study, that included the analysis of cognitive tasks performance, event-related potentials and psychometric scales, has been conducted.Materials
A. V. Kirenskaya +4 more
doaj +1 more source
p300/CBP and p300/CBP-associated Factor with Transcriptional Regulation
, 2009 P300/CbP及其相关因子PCAf具有乙酰转移酶活性,能通过乙酰化组蛋白和非组蛋白的方式参与基因的转录调控.同时,它们也能介导多种转录因子.与大多数典型的转录辅激活子相同,它们能在转录因子和基本转录复合物之间起到桥梁作用.P300/CbP与细胞周期调控、细胞凋亡以及癌症的发生等过程之间有着直接的联系.本文概括介绍了P300/CbP与PCAf的基本特性,并简要介绍它们与其它蛋白之间的相互作用,特别是E1A的最新研究进展.p300/CBP and p300/CBP-associated factor ...
林娟玉, 黄翔, 韩爱东
core
p300 HAT activation is decreased in pFb vs. SF-Fb.
, 2014 A). PMA-induced p300 HAT activity in untransfected native cells. Upper panel shows p300 proteins analyzed by Western blotting and lower panel, p300 HAT activity. B). p300 HAT activity in p300-transfected fibroblasts. Upper panel shows p300 proteins in Fb
Kenneth K. Wu (154996) +5 more
core +1 more source
Food Frontiers, Volume 7, Issue 4, July 2026.Soybean‐derived exosome‐like nanovesicles suppress lipid accumulation of adipocytes via UCP1/PGC‐1α mediated thermogenesis pathway and boosting mitochondrial function. ABSTRACT Obesity has become an important public health concern in modern society. Plant‐derived exosome‐like nanovesicles are emerging as candidates for obesity intervention.
Zhenzhu Zhu +5 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 1, Page 144-158, 1 July 2026.What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source
DDX21 Promotes Breast Cancer Growth and Metastasis via Stimulating RNAPII Elongation During Hypoxia
MedComm, Volume 7, Issue 7, July 2026.DDX21 triggers CDK9 release from the 7SK RNP complex. DDX21‐CDK9 binding to HIFs drives transcriptional reprogramming during hypoxia. DDX21 enhances breast cancer progression and metastasis. Elevated DDX21 expression correlates with poor prognosis in breast cancer patients.
Guangqiang Li +11 more
wiley +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Protein Science, Volume 35, Issue 7, July 2026.Abstract Recent advances in predicting and modeling conformational ensembles of intrinsically disordered proteins (IDPs) have provided much needed insights into sequence‐ensemble relationships. It is thought that conservation of physicochemical properties, but not the exact identity or order of the amino acids, maintains IDP ensemble properties that ...
To Uyen Do +4 more
wiley +1 more source
Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia
Clinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise +5 more
wiley +1 more source