Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao +5 more
wiley +1 more source
A Novel Anti-Fibrotic Role of G-Protein-Coupled Receptor 119 in Hepatic Stellate Cells. [PDF]
Biomol Ther (Seoul)Park J +6 more
europepmc +1 more source
Inducible CRISPR/Cas systems in precision oncology: Current applications and future perspectives
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.Inducible CRISPR/Cas systems enable spatiotemporal genome editing in precision oncology. Chemical, optical, physical, and microenvironmental stimuli provide distinct control strategies. Conditional activation may reduce off‐target exposure and basal nuclease activity.
Ziliang Ding +3 more
wiley +1 more source
Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment
Exploration, Volume 6, Issue 3, June 2026.This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng +11 more
wiley +1 more source
Enhancing Oncolytic Adenovirus Replication by Early Region 1A Protein-Mediated Degradation of E1A Binding Protein p300. [PDF]
MedComm (2020)Xiao B +7 more
europepmc +1 more source
Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven <i>KLF6</i> expression in renal carcinoma. [PDF]
Oncol RepZamberi NNM +5 more
europepmc +1 more source
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background and Aims Leukemia is a heterogeneous group of hematologic malignancies influenced by both genetic and environmental factors. The B‐cell‐specific Moloney murine leukemia virus integration site 1 (BMI1) gene, a key regulator of hematopoietic stem cell self‐renewal and oncogenesis, has been implicated in leukemia pathogenesis.
Mojtaba Aghaei +2 more
wiley +1 more source
The effect of brain-computer interface training on cognitive function in stroke patients: a systematic review and meta-analysis. [PDF]
J NeurolFan Y +5 more
europepmc +1 more source
Roles of histone lysine methylation in neurodevelopment and related disorders
Ibrain, Volume 12, Issue 2, Page 201-221, Summer 2026.This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen +3 more
wiley +1 more source
An intelligent EEG-based ensemble framework for communication assistance in Locked-In Syndrome patients. [PDF]
Sci RepSelvam AK, Loganathan A.
europepmc +1 more source