Results 51 to 60 of about 77,303 (286)

P300 Component Modulation During a Go/Nogo Task in Healthy Children

open access: yesBasic and Clinical Neuroscience, 2010
Introduction: Several differences in the P300 component are observed when responses must be executed or inhibited in the Go/Nogo task. However, few studies were established by using well-controlled task with respect to the preparatory processing and ...
Mohammad Ali Nazari   +4 more
doaj   +2 more sources

Loss of p300 in proximal tubular cells reduces renal fibrosis and endothelial-mesenchymal transition

open access: yesEMBO Molecular Medicine
Chronic kidney disease (CKD) has a high prevalence worldwide and is typically accompanied by severe fibrosis. However, the exact pathogenesis of renal fibrosis and effective treatments have yet to be identified. In this study, we found that expression of
Hyunsik Kim   +9 more
doaj   +1 more source

Cerebral networks linked to the event-related potential P300 [PDF]

open access: yes, 2003
P300 is an event-related potential that is elicited by an oddball paradigm. In several neuropsychiatric diseases, differences in latencies and amplitude compared to healthy subjects have been reported.
Horn, H   +4 more
core   +2 more sources

Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents [PDF]

open access: yes, 2022
The histone acetyltransferases CBP and p300, often referred to as CBP/p300 due to their sequence homology and functional overlap and co-operation, are emerging as critical drivers of oncogenesis in the past several years.
Liu, X   +5 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

An analysis of the accuracy of the P300 BCI [PDF]

open access: yesBrain-Computer Interfaces, 2018
The P300 Brain-Computer Interface (BCI) is a well-established communication channel for severely disabled people. The P300 event-related potential is mostly characterized by its amplitude or its area, which correlate with the spelling accuracy of the P300 speller.
Nitzan S. Artzi, Oren Shriki
openaire   +3 more sources

Elucidating different aspects of speed of information processing: comparison of behavioral response latency and P300 latency in a modified Hick reaction time task [PDF]

open access: yes, 2016
The aim of the present work was to get a more detailed understanding of the functional significance of the P300 latency. P300 latency is often used as measure of stimulus evaluation time. However, the interpretation of P300 latency as stimulus evaluation
Merks, Sarah
core   +2 more sources

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

open access: yesAdvanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan   +17 more
wiley   +1 more source

p300 upregulates Ikur in atrial cardiomyocytes through activating NLRP3 inflammasome in hypertension

open access: yesChinese Medical Journal
. Background:. The nucleotide-binding oligomerization domain [NOD-], leucine-rich repeats [LRR-], and Pyrin domain-containing protein 3 (NLRP3) inflammasome plays an essential role in hypertension-related atrial fibrillation (AF).
Long Zeng   +15 more
doaj   +1 more source

Potencial evocado cognitivo e desordem de processamento auditivo em crianças com distúrbios de leitura e escrita Cognitive evoked potentials and central auditory processing in children with reading and writing disorders

open access: yesBrazilian Journal of Otorhinolaryngology, 2012
As dificuldades na aprendizagem escolar muitas vezes podem ser causadas por uma alteração do Processamento Auditivo - PA. OBJETIVO: Identificar se acima da média dos valores de latência do P300, num grupo de indivíduos com Distúrbio de Leitura e Escrita,
Gislaine Richter Minhoto Wiemes   +4 more
doaj   +1 more source

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