Results 41 to 50 of about 68,762 (209)
Dysregulation of oncogenic factors by GFI1B p32: investigation of a novel GFI1B germline mutation
Haematologica, 2021 GFI1B is a transcription factor essential for the regulation of erythropoiesis and megakaryopoiesis, and pathogenic variants have been associated with thrombocytopenia and bleeding.
Michela Faleschini +11 more
doaj +1 more source
On the one loop $\gamma^{(*)}\to q\bar{q}$ impact factor and the exclusive diffractive cross sections for the production of two or three jets [PDF]
, 2016 We present the calculation of the impact factor for the $\gamma^{(*)}\to q\bar{q}$ transition with one loop accuracy in arbitrary kinematics. The calculation was done within Balitsky's high energy operator expansion. Together with our previous result for
Boussarie, R. +3 more
core +2 more sources
Cells, 2020 Arginase II reciprocally regulates endothelial nitric oxide synthase (eNOS) through a p32-dependent Ca2+ control. We investigated the signaling pathway of arginase II-dependent eNOS phosphorylation. Western blot analysis was applied for examining protein
Bon-Hyeock Koo +3 more
doaj +1 more source
p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditure
Scientific Reports, 2017 Obesity is increasing in prevalence and has become a global public health problem. The main cause of obesity is a perturbation in energy homeostasis, whereby energy intake exceeds energy expenditure.
Yong Liu +5 more
doaj +1 more source
Impaired p32 Regulation Caused by the Lymphoma-Prone RECQ4 Mutation Drives Mitochondrial Dysfunction
Cell Reports, 2014 Mitochondrial DNA (mtDNA) encodes proteins that are important for ATP biogenesis. Therefore, changes in mtDNA copy number will have profound consequences on cell survival and proliferation.
Jiin-Tarng Wang +4 more
doaj +1 more source
Annals of Neurology, EarlyView.Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral +52 more
wiley +1 more source
The process of infection with bacteriophage phiX174, XXX. Replication of double-stranded phiX DNA [PDF]
, 1969 Intermediates involved in the replication of double-stranded phiX174 RF DNA have been identified and partially characterized. Analysis of pulse-labeled RF DNA suggests that the synthesis of progeny RF molecules involves, in part, the addition of ...
Knippers, Rolf +2 more
core
A snoRNA modulates mRNA 3' end processing and regulates the expression of a subset of mRNAs. [PDF]
, 2017 mRNA 3' end processing is an essential step in gene expression. It is well established that canonical eukaryotic pre-mRNA 3' processing is carried out within a macromolecular machinery consisting of dozens of trans-acting proteins. However, it is unknown
Ding, Junjun +14 more
core +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Quantitative methods that have evaluated the Eating Disorder Examination Questionnaire (EDE‐Q) have found consistent evidence that the original four‐factor structure does not replicate across diverse samples and genders. Emerging evidence in the broader psychology literature shows that qualitative methods can provide nuanced insight ...
Katarina L. Huellemann +3 more
wiley +1 more source
Journal of Biomedical ScienceBackground Mutations in CHCHD2 have been linked to Parkinson’s disease, however, their exact pathophysiologic roles are unclear. The p32 protein has been suggested to interact with CHCHD2, however, the physiological functions of such interaction in the ...
Murni Tio +8 more
doaj +1 more source