Results 291 to 300 of about 281,509 (352)

The p38 signal transduction pathway Activation and function

Cellular Signalling, 2000
Jiahuai Han, Koh Ono
exaly   +2 more sources

Exposure to polystyrene microplastics causes reproductive toxicity through oxidative stress and activation of the p38 MAPK signaling pathway.

Ecotoxicology and Environmental Safety, 2019
Microplastics (MP) are receiving increased attention as a harmful environmental pollutant, however information on the reproduction toxicity of MP in terrestrial animals, especially mammals, is limited.
Xiaoman Xie, Ting Deng, Jiufei Duan, Jing Xie, Junlin Yuan, Mingqing Chen   +5 more
semanticscholar   +1 more source

Benzimidazolone p38 inhibitors

Bioorganic & Medicinal Chemistry Letters, 2004
The synthesis and in vitro p38 alpha activity of a novel series of benzimidazolone inhibitors is described. The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors ...
Mark A, Dombroski, Michael A, Letavic, Kim F, McClure, John T, Barberia, Thomas J, Carty, Santo R, Cortina, Csilla, Csiki, Alan J, Dipesa, Nancy C, Elliott, Christopher A, Gabel, Crystal K, Jordan, Jeff M, Labasi, William H, Martin, Kevin M, Peese, Ingrid A, Stock, Linne, Svensson, Francis J, Sweeney, Chul H, Yu   +17 more
openaire   +2 more sources

Role of p38/MAPKs in Alzheimer’s disease: implications for amyloid beta toxicity targeted therapy

Reviews in the Neurosciences, 2018
A myriad of environmental and genetic factors, as well as the physiologic process of aging, contribute to Alzheimer’s disease (AD) pathology. Neuroinflammation is and has been a focus of interest, as a common gateway for initiation of many of the ...
Ghazaleh Kheiri, Mahsa Dolatshahi, Farzaneh Rahmani, N. Rezaei   +3 more
semanticscholar   +1 more source

P38

Oral Diseases, 2005
Transferred to oral ...
openaire   +1 more source

p38 activation and viral infection

Expert Reviews in Molecular Medicine, 2022
AbstractViruses completely rely on the energy and metabolic systems of host cells for life activities. Viral infections usually lead to cytopathic effects and host diseases. To date, there are still no specific clinical vaccines or drugs against most viral infections. Therefore, understanding the molecular and cellular mechanisms of viral infections is
Luyao, Wang, Zhiqiang, Xia, Wei, Tang, Yu, Sun, Yingliang, Wu, Hang Fai, Kwok, Fang, Sun, Zhijian, Cao   +7 more
openaire   +2 more sources

p38

Surgery for Obesity and Related Diseases, 2006
Marlene M. Silva, Celina D.B. Sobreira, Alexandre Capeletto, Marta Magalinski, Cristiane E. Machado, Bruno Zilberstein, Denis Pajecki, Joel Faintuch   +7 more
  +4 more sources

P38

Journal of Surgical Research, 2007
S. Yeluri, N. Muthukumar, N.J. London
  +4 more sources