Results 281 to 290 of about 205,636 (290)

p38 MAPK inhibitors in dermatology

Expert Review of Dermatology, 2007
p38 mitogen-activated protein kinase (MAPK) is involved in regulating cell growth, cell differentiation, cell proliferation, cell apoptosis and response to inflammation and stress. Four mammalian p38 MAPK isoforms, p38 MAPKα, p38 MAPKβ, p38 MAPKγ (ERK6/SAPK3) and p38 MAPKδ (SAPK4), have been identified.
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Stress-induced interaction between p38 MAPK and HSP70

Biochemical and Biophysical Research Communications, 2012
p38 MAPK, one of the four MAPK subfamilies in mammalian cells, is activated by environmental stresses and pro-inflammatory cytokines, playing fundamental roles in many biological processes. Despite all that is known on the structure and functions of p38, many questions still exist.
Xiaowei, Gong, Tingting, Luo, Peng, Deng, Zhenxi, Liu, Jiancheng, Xiu, Hongqin, Shi, Yong, Jiang   +6 more
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Roles of p38 MAPKs in invasion and metastasis

Biochemical Society Transactions, 2012
Cells from primary tumours need to go through several steps to become fully metastatic. During this process, cancer cells acquire the ability to invade, migrate across the surrounding tissue, enter into the circulation and colonize distant organs. In the present paper, we review recent progress in understanding how the p38 MAPK (mitogen-activated ...
Barrantes, Ivan Del Barco, Nebreda, Angel R.   +1 more
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CyHV-2 ORF104 activates the p38 MAPK pathway

Fish & Shellfish Immunology, 2015
Cyprinid herpesvirus 2 (CyHV-2) is the pathogen responsible for herpesviral hematopoietic necrosis disease, which causes huge losses on aquaculture. So far the studies of CyHV-2 mainly focus on the identification and detection of this virus, but little is known about the role of specific CyHV-2 genes in the infection process.
Mi, Du, Mingliang, Chen, Haifeng, Shen, Wei, Wang, Zengpeng, Li, Weiyi, Wang, Jianhui, Huang, Jianming, Chen   +7 more
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Pharmacological Potential of p38 MAPK Inhibitors

2005
A key component of the intracellular signaling pathways involved in cellular response to environmental stress and inflammatory cytokines is the p38 family of mitogen-activated protein kinases (MAPKs). Of the four isoforms of the p38 family of MAPKs identified thus far, p38α is the most characterized enzyme.
S. Kumar, S. M. Blake
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p38 Gamma MAPK

2016
Xiao-Mei Qi, Fang Wang, Guan Chen
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p38 MAPK Family

2017
John Papaconstantinou, Ching-Chyuan Hsieh, James H. DeFord   +2 more
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Mechanisms of MAPK kinase-independent p38-MAPK activation

Journal of Molecular and Cellular Cardiology, 2008
Rekha Bassi, Richard Heads, Michael Marber   +2 more
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p38 MAPK

2009
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P38 MAPK

2013
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