Results 51 to 60 of about 213,688 (282)

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

open access: yesAdvanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett   +19 more
wiley   +1 more source

On extended P4-reducible and extended P4-sparse graphs

open access: yes, 1997
A graph G was defined in [16] as P4-reducible, if no vertex in G belongs to more than one chordless path on four vertices or P4. A graph G is defined in [15] as P4-sparse if no set of five vertices induces more than one P4, in G.
Giakoumakis, Vassilis   +1 more
core   +1 more source

Resolving the Cu(bdc) Conundrum: Identifying Non‐Porous Packing of Prototypical Coordination‐Network Thin Films Combining Advanced Diffraction Techniques and Computational Modelling

open access: yesAdvanced Functional Materials, EarlyView.
Solution‐processed Cu(bdc) forms prototypical MOF thin films for which a multitude of not fully satisfactory structural models have been suggested. Combining rotating grazing‐incidence diffraction and X‐ray reflectivity on two complementary samples with density‐functional theory, we first discard the previously suggested models and then identify a non ...
Narges Taghizade   +7 more
wiley   +1 more source

Dynamic Interfacial Chemistry of Choline Chloride as Electrolyte Additive for Stable Zn‐Iodine Batteries

open access: yesAdvanced Functional Materials, EarlyView.
Choline chloride (ChCl) additive enables dynamic interface engineering in Zn‐I2 batteries by forming hydrophobic polyiodide complexes and a Zn‐stabilizing Ch+‐rich layer under electric field modulation. This dual‐function strategy suppresses iodine hydrolysis and dendrite formation, while optimizing Zn2+ solvation and transport for high‐efficiency ...
Xiaoyu Bi   +16 more
wiley   +1 more source

Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies

open access: yesNature Communications, 2018
Optimization of antiviral therapy can be crucial in the management of Ebola virus outbreaks. Here, Madelain et al. use an integrative mathematical model to correlate the dose and the time of treatment initiation with survival rate, enhanced immune ...
Vincent Madelain   +12 more
doaj   +1 more source

Solvent‐Free Thermal Defect Engineering in Molecular Frameworks With Volatile Linkers

open access: yesAdvanced Materials, EarlyView.
Thermal removal of neutral volatile linkers enables precise and solvent‐free generation of metal vacancies in MOFs. This strategy affords redox‐stable, coordinatively unsaturated FeII sites with tunable spin, ligand coordination, and catalytic behavior. The approach offers a general route to design defect‐functional materials through local coordination
Sonia Martínez‐Giménez   +9 more
wiley   +1 more source

Grundy number on P4-classes

open access: yes, 2009
International audienceIn this article, we define a new class of graphs, the fat-extended P4 -laden graphs, and we show a polynomial time algorithm to determine the Grundy number of the graphs in this class.
Araujo, Julio   +3 more
core   +1 more source

A Reproducible and Scalable Process for High Yield Mesenchymal Stromal Cell Extracellular Vesicles Production

open access: yesAdvanced Materials Technologies, EarlyView.
Mesenchymal stem cell derived extracellular vesicles (MSC‐EVs) are a promising therapeutic tool for regenerative medicine. However, the field lacks a reproducible high‐yield production method to answer the quantities needed for clinical translation.
Christophe Wong   +7 more
wiley   +1 more source

Implementation and Evaluation of Activity-Based Congestion Management Using P4 (P4-ABC)

open access: yesFuture Internet, 2019
Activity-Based Congestion management (ABC) is a novel domain-based QoS mechanism providing more fairness among customers on bottleneck links. It avoids per-flow or per-customer states in the core network and is suitable for application in future 5G ...
Michael Menth   +3 more
doaj   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

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