Results 101 to 110 of about 1,026,956 (152)

[Germline DDX41 mutations and myelodysplastic neoplasms]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhong Y, Xiao ZJ.
europepmc   +1 more source

Synthetic lethality by lentiviral short hairpin RNA silencing of thymidylate kinase and doxorubicin in colon cancer cells regardless of the p53 status.

, 2015
[[sponsorship]]基因體研究中心[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Drexel&SrcApp=hagerty_opac&KeyRecord=0008-5472&DestApp=JCR&RQ ...
Hu, CM;Chang, ZF
core  

[Novel CD6-targeted CAR-T cell therapy for T-cell acute lymphoblastic leukemia: a safe and efficient strategy to prevent fratricide through gene editing]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Shangguan YT, Xie LL, Liu WB, Gu RX, Xu YX, Wang M, Wang JX.   +6 more
europepmc   +1 more source

Genetic polymorphisms of p53 and GSTP1, but not NAT2, are associated with susceptibility to squamous-cell carcinoma of the esophagus

, 2013
[[sponsorship]]基因體研究中心[[note]]已出版;[SCI];沒有審查制度;不具代表性[[note]]http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Drexel&SrcApp=hagerty_opac&KeyRecord=0020-7136&DestApp=JCR&RQ=IF_CAT_BOXPLOT[[note]]http://gateway.isiknowledge.com ...
Lee, J. M.;Lee, Y. C.;Yang, S. Y.;Shi, W. L.;Lee, C. J.;Luh, S. P.;Chen, C. J.;Hsieh, C. Y.;Wu, M. T.
core  

[Research progress on cellular senescence and liver diseases]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Zhang LT, Hu JM, Wang JW, Li H, Qin YJ.
europepmc   +1 more source

四膜虫rDNA表达载体的改造及用于异源基因的高效表达

, 2013
基于四膜虫小核rDNA改造得到的pD5H8载体，在转染进接合生殖时期的四膜虫后能发育成9000～10000拷贝的大核rDNA，因此pD5H8载体是四膜虫异源基因表达的研究热点；但其载体上匮乏合适的克隆位点和无启动子结构阻碍了该载体的进一步发展。本研究在四膜虫启动子HSP70—2和终止子HSP70-I之间，通过稀有酶切位点I-SceI导入细菌绿色荧光蛋白NGFP）这一筛选标记，由此组成的DNA片段（HSP70-25’UTR．I-SceI—HGFP．I—SeeI—HSP70-13’UTR）整合进pD5H8 ...
冯立芳, 熊杰, 袁冬霞, 缪炜
core  

[<i>Qihuang Jianpi Zishen</i> Granule ameliorates renal injury in patients with systemic lupus erythematosus by regulating immunometabolic reprogramming of macrophages]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Qian A, Huang C, Zhu Y, Hu K, Song X, Xu Y.   +5 more
europepmc   +1 more source

转基因鱼的研究进展

, 1999
自１９８４ 年第一例转基因鱼在我国诞生以来，转基因鱼研究取得长足进步。研究表明外源基因可以整合、表达，并能遗传给后代，然而外源基因整合位点难以控制，遗传不稳定等问题仍未解决。所幸我国鱼类核移植技术较为成熟，结合细胞基因转移、基因打靶和核移植技术 ...
赵浩斌,陈尚萍,朱作言
core  

[<i>Jintiange</i> Capsule alleviates glucocorticoid-induced osteoporosis in rats by inhibiting vascular endothelial cell senescence and promoting bone formation]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Deng Z, Wang Z, Meng S, Yang Y, Yang Y, Fan L, Wang L.   +6 more
europepmc   +1 more source

Distinct p53-mediated G1/S checkpoint responses in two NIH3T3 subclone cells following treatment with DNA-damaging agents.

, 2013
[[sponsorship]]基因體研究中心[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Drexel&SrcApp=hagerty_opac&KeyRecord=0950-9232&DestApp=JCR&RQ=IF_CAT_BOXPLOT[[note]]http://gateway.isiknowledge.com/gateway ...
Huang, TS;Kuo, ML;Shew, JY;Chou, YW;Yang, WK
core