Results 1 to 10 of about 18,633 (119)
Zhongguo cuzhong zazhi, 2022 目的 探究散发性脑动静脉畸形组织中Kirsten大鼠肉瘤病毒癌基因同源物（Kirsten rat sarcoma viral oncogene homolog，KRAS）突变与临床特征之间的关系。 方法 回顾性收集散发性动静脉畸形（brain arteriovenous malformation，BAVM）术后病变组织的福尔马林固定石蜡包埋（formali n-fixation and paraffin-embedding，FFPE）样本和对应患者的临床信息，从FFPE样本中提取DNA ...
李昊, 许宏远, 押小龙, 曹勇
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Zhongguo shiyan zhenduanxue, 2022 目的 分析中国西北地区汉族苯丙酮尿症（PKU）患者苯丙氨酸羟化酶（PAH）基因的突变特征。方法 应用PCR产物直接测序法对2003年1月-2019年8月在中国西北五省区新生儿疾病筛查中心或医学遗传中心确诊的223例汉族PKU患儿及其父母的PAH基因启动子、第1-13外显子及其旁侧内含子区域进行基因突变分析。结果在西北地区223例汉族PKU患者446条PAH等位基因中检测出75种致病突变，总检出率为88.6%(395/446)，突变以错义突变（66.7%）、剪切位点突变（16.0%）和无义突变（9.3 ...
何江 +6 more
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血小板源性生长因子受体α突变型胃肠间质瘤的临床病理特征及预后分析
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的探讨血小板源性生长因子受体α（PDGFRA）突变胃肠道间质瘤（GIST）中PDGFRA基因的突变状况、临床病理特征及预后因素，为生物靶向治疗提供依据。方法收集 2015 年1月至 2020 年11月期间中山大学肿瘤防治中心收治的经病理确诊为GIST，且原发肿瘤组织通过Sanger测序证实存在PDGFRA基因12或18号外显子突变的40例患者石蜡标本。采用免疫组化检测GIST中CD117、CD34、DOG-1及Ki-67表达情况。收集患者临床病理特征资料，回顾性分析影响 PDGFRA 突变型GIST ...
吴小延 +5 more
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高变异Y染色体短串联重复片段检验体系的建立及对北方汉族群体调查
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的建立一套五色荧光复合扩增体系，并调查中国北方汉族遗传多态性和父子家系突变情况。方法根据文献筛查出在中国某一群体中突变率为高变异和快速变异的Y-STR基因座，建立一套五色荧光Y-STR复合扩增体系，计算在500个北方汉族无关男性个体中的基因多样性，观察每个样本的Y-STR单倍型，并对中国北方汉族500个父子对进行检测，统计父子间的突变情况。结果成功构建了包含21个Y-STR基因座复合扩增检验体系，在北方汉族群体中基因多态性在0.402 3～0.990 4之间，500个无关个体中未发现有相同的单倍型 ...
李运丽 +6 more
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International Journal of Applied Linguistics, EarlyView.ABSTRACT Multilingual students in Anglophone universities often operate in survival mode. While translanguaging supports learning, critical gaps remain in understanding how translanguaging pedagogies transform and sustain motivation in English‐dominant contexts.
Melissa Jufenna Slamet, Julie Choi
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Coalition Breakdown and Subsystem Exit
Policy Studies Journal, EarlyView.ABSTRACT Why actors choose to work together (or not) to advance policy has been the central area of inquiry within the Advocacy Coalition Framework (ACF). Existing research has mainly emphasized the pathway towards coalition formation and evolution, underscoring the stable patterns of allies and opponents observable in policy processes over a decade or
Charlie F. Thompson
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World Water Policy, Volume 12, Issue 3, August 2026.ABSTRACT Village tank cascade systems (VTCS) are a long‐established form of water management in Sri Lanka's dry zone. However, their role in groundwater recharge, climate adaptation, and water governance remains insufficiently recognized in policy and planning.
Ananthini Nanthakumaran +1 more
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New Phytologist, Volume 251, Issue 3, Page 1283-1293, August 2026.Polyphenol oxidases (PPOs) depletion preserves endogenous proteins at their predicted molecular weights and enhances detectable enzymatic activities. (a) Less RbcL crosslinking in ppo mutant of Nicotiana benthamiana. Leaf extracts were incubated for 1 h, separated on protein gels, stained with Coomassie or analyzed by Western blot with the anti‐RbcL ...
Kaijie Zheng +4 more
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Powerful representation of the poor? German welfare associations' narrative advocacy during COVID‐19
Policy Studies Journal, Volume 54, Issue 3, August 2026.Abstract The COVID‐19 pandemic sparked unprecedented experimentation in the German social assistance system, leading to changes previously considered impracticable by policymakers. This included a sanctions moratorium, easier access to benefits, and temporary cash transfers, all of which were advocated by welfare associations—key organized interests ...
Christopher Smith Ochoa
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Justice in coexistence: Pastoralism and large carnivores on the Qinghai‐Tibet Plateau
People and Nature, Volume 8, Issue 7, Page 2186-2199, July 2026.Abstract The conflict between livestock husbandry and large carnivore conservation presents significant challenges in grassland ecosystems worldwide. Achieving sustainable coexistence among herders, livestock and large carnivores requires reconciling diverse perspectives and interests through equitable, inclusive and fair processes that address both ...
Yufang Gao, Yue Yu
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