Results 41 to 50 of about 24,523 (167)
Political Trust and Aspirations to Influence Social Media During a Crisis: A Longitudinal Study
Policy &Internet, Volume 18, Issue 1, March 2026.ABSTRACT This study investigated how political trust shaped citizens' aspirations to influence others on social media during a COVID‐19 pandemic. Using four‐wave longitudinal survey data (2017–2021; N = 2172) collected from 543 citizens in Finland, we first analysed how political trust moderated the temporal development of individuals' aspirations to ...
Aki Koivula +2 more
wiley +1 more source
Plasma microRNA Associated with EGFR-TKI Primary Resistance in Non-Small Cell Lung Cancer with EGFR-Mutation [PDF]
, 2016 背景 肺癌是目前全世界范围内发病率和死亡率较高的恶性肿瘤之一。按组织学分类，肺癌可以分为两大类：小细胞肺癌（smallcelllungcancer，SCLC）和非小细胞肺癌（nonsmallcelllungcancer，NSCLC），小细胞肺癌占所有病例的20%，其余80%左右为NSCLC，包括鳞癌、腺癌、大细胞癌等类型。手术、放疗以及化疗等多学科综合治疗是指南推荐的NSCLC的首选治疗方式。由于NSCLC早期的典型临床症状和体征并不明显，约2/3的NSCLC患者在确诊时已发展为中晚期，失去手术根治机会。
潘小艳
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Devouring the Invaders: The Racial‐Ecological Politics of the Chinese Crayfish Trade in Kenya
American Anthropologist, Volume 128, Issue 1, Page 183-194, March 2026.ABSTRACT This article examines entanglements of ecology, race, and foodways at Lake Naivasha in Kenya. Nonnative Louisiana red swamp crayfish (Procambarus clarkii), first introduced to Kenya in the 1960s, were once viewed as invasive but are now sought after as a delicacy among Kenya's Chinese community.
Amanda Kaminsky
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2012 目的对已明确基因突变的轻型β-珠蛋白生成障碍性贫血患者的红细胞参数进行比较分析,探讨β-珠蛋白基因的突变类型与红细胞参数的相关性。方法分析118例已知基因突变的轻型β-珠蛋白生成障碍性贫血患者的红细胞平均容积、红细胞平均血红蛋白含量、红细胞平均血红蛋白浓度、红细胞体积分布宽度标准差、红细胞体积分布宽度变异系数,对这些参数依据突变类型进行比较。结果在已知β-珠蛋白基因突变中,携带codon41/42（-TTCT）突变的患者红细胞平均容积、红细胞平均血红蛋白含量及红细胞平均血红蛋白浓度高于其它突变患者 ...
彭运生 +4 more
doaj
A preliminary study on mechanisms of fission yeast Dnt1 participating in accurate chromosome segregation and efficient G2/M transition [PDF]
, 2016 在裂殖酵母中，Dnt1主要定位在核仁里，在有丝分裂后期还定位在纺锤体上。本实验室之前的研究发现，Dnt1对于纺锤体检验点的沉默是必需的；另外Dnt1通过下调Wee1蛋白水平调控细胞G2/M转换以及胞质分裂。 本研究通过对染色体分离情况的精确观察，我们发现Dnt1与Monopolin蛋白(Pcs1/Mde4)、AuroraB激酶Ark1分别通过不同途径防止姊妹染色体的merotelicorientation，在染色体准确分离过程中起着重要作用。利用nda3-KM311cdc13-GFPark1 ...
陈丽华
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Governance of Climate‐Induced Relocation in the US: An Exploration of Institutional Complexity
Review of Policy Research, Volume 43, Issue 2, March 2026.ABSTRACT Climate change has and will continue to have a profound effect on both individuals and the communities in which they reside. A pressing question is how communities forced to confront climate‐induced catastrophe—including both rapid and slow‐onset hazards—undertake the decision of how and when to relocate, particularly given the multiple scales
Christopher S. Galik, Brad A. Johnson
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2003 目的 探讨 10例遗传性凝血因子Ⅶ （coagulationfactorⅦ ,FⅦ ）缺陷症基因突变类型与临床特性。方法 检测凝血指标以明确诊断 ;用DNA直接测序法对先证者及其家庭成员FⅦ基因的全部外显子及其侧翼、5’和 3’非翻译区进行分析 ,寻找基因突变 ;将含插入或缺失突变序列克隆入pMD18 TTA克隆载体中 ,对所得两条染色体相应序列分别测序 ,以确定突变在染色体上的分布。应用限制性内切酶对先证者及家系成员相应基因片段进行酶切分析 ,无酶切位点改变的基因片段用等位基因特异的PCR（ASPCR）
丁秋兰 +7 more
doaj
Functional Characterization of AtST39 in Stress Response and AtMPA Mediating Pollen Development [PDF]
, 2012 基因芯片显示番茄细菌性叶斑病原菌Pseudomonassyringaepv.tomatoDC3000(PstDC3000)，干旱、冷和盐等逆境处理及在开花关键基因lfy突变体中都能够上调AtST39（At3g46110）基因表达；AtMPA（At1g05577）在拟南芥单核花粉粒向三核花粉发育的过程中特异性表达。但是AtST39参与胁迫和AtMPA在介导花粉发育的分子机制知之甚少。我们主要对AtST39进行了探索研究，结果如下： （1）NCBI数据库显示YWC基因家族共有185个蛋白家族成员 ...
肖世民
core
Review of Policy Research, Volume 43, Issue 2, March 2026.ABSTRACT The future of work (FoW), that is, how new technologies from automation to artificial intelligence affect the workplace, has become such a salient topic that its framing matters for the evolution of important policy areas from social protection to market and labor regulation.
Achim Kemmerling, Viddy Ranawijaya
wiley +1 more source
A preliminary study on Wee1 kinase protein stability in fission yeast [PDF]
, 2016 Wee1作为真核生物中调控细胞有丝分裂G2/M期过渡的重要激酶，它的功能可以被Cdc25磷酸酶所拮抗。如果细胞中的Wee1蛋白水平或者活性过高，细胞进入有丝分裂期延迟；而反之则G2期缩短，细胞提前进入有丝分裂期，因此在整个细胞周期中Wee1受到了非常精细地调控。高等生物中的研究表明，Wee1蛋白水平和稳定性受到了SCF的调控。为了研究裂殖酵母中参与调控Wee1激酶蛋白水平的细胞因子，本研究以裂殖酵母这一经典的单细胞真核生物为模式生物，开展了对有丝分裂G2/M过渡时期参与调控Wee1蛋白水平的因子的研究。
邱翠
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