Results 111 to 120 of about 1,318 (154)

[Advances in basic and experimental diagnostic research on liver diseases in 2025​]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Chen DB, Yang RF, Chen HS.
europepmc   +1 more source

黄芪甲苷通过抑制STING通路减轻D-半乳糖诱导的心肌细胞衰老和凋亡

Zhongshan Daxue xuebao. Yixue kexue ban
目的探讨黄芪甲苷（AS-Ⅳ）对D-半乳糖（D-gal）诱导的心肌细胞衰老的保护作用及其潜在机制。方法以心肌细胞H9C2为模型，采用D-gal诱导心肌细胞衰老，通过CCK-8法检测细胞活力，β-半乳糖苷酶（SA-β-Gal）染色评估细胞衰老程度，ROS检测细胞内活性氧水平，TUNEL检测细胞凋亡程度，qRT-PCR和Western blot检测衰老相关基因和蛋白（p21、p53）及干扰素基因刺激因子（STING）通路关键基因（STING、CXCL10和 MX-1）和蛋白（STING、cGAS、p-IRF3/
郭文玉, 高佳佳, 段玮丽, 阮焕钧, 黄于朗, 王珂妹, 柯晓   +6 more
doaj  

[Advances on efficacy and mechanisms of acid fibroblast growth factor for promoting injured tissue repair]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhu F, Jiang Z, Qian X, Xu Y, Cheng H, Zhang J.   +5 more
europepmc   +1 more source

[PINK1 suppresses colorectal cancer cell growth through epigenetic regulation of histone modifications]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Wang M, Luan S, Fan X, Han D, Zhu Y.
europepmc   +1 more source

[<i>MUTYH-APEX1</i> Axis Promotes Hepatocellular Carcinoma Progression and Therapeutic Resistance by Regulating Cell Cycle Proteins]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Zhou Y, Zhang H, Zhu Y, Jiang P, Feng T, Wu Z, Chen J.   +6 more
europepmc   +1 more source

基于免疫组化法三阴性乳腺癌分型及其预后研究

Zhongguo shiyan zhenduanxue
目的探讨基于免疫组化法的三阴性乳腺癌（TNBC）分子分型，观察不同分子分型患者的临床病理特征及预后差异。方法根据雄激素受体（AR）、分化簇8（CD8）、叉头框蛋白C1（FOXC1）、双皮质素样激酶1(DCLK1）免疫组化表达情况进行分子分型，比较各亚型间临床、病理特征及预后差异。结果110例TNBC中腔面雄激素受体亚型35例（31.8%），免疫调节亚型24例（21.8%），基底样免疫抑制型34例（30.9%），间充质亚型17例（15.5%）。各亚型之间临床病理特征中组织学分级（P<0.001 ...
陈菊华, 阚炳华, 张宏伟, 宋琦, 陈曦, 白宁   +5 more
doaj  

[CAR-T cell therapy bridging to allogeneic hematopoietic stem cell transplantation for diffuse large B-cell Richter syndrome: a case report and literature review]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Wang Y, Gao N, Liu ZY, Dong YY, Qin XM, Liu X.   +5 more
europepmc   +1 more source

[Identification of SORD as A Key Gene Mediating Osimertinib Primary Resistance 
in EGFR-Mutant Lung Adenocarcinoma via Machine Learning and Methylomics]. [PDF]

Zhongguo Fei Ai Za Zhi
Liang G, Wu H, Jia C, Gao P, Zhang Z, Chen C, Li Y, Liu H, Chen J.   +8 more
europepmc   +1 more source

[Acupuncture alleviates chronic airway inflammation in obese asthmatic mice by downregulating Vnn1 and FAM126B]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li X, Ye T, Xi L, Li C, Liu H.
europepmc   +1 more source

[The clinical study of azacitidine and lenalidomide combination in myelodysplastic neoplasm patients with TP53 mutations]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Yan X, Guo CH, Yang C, Lin CQ, Song DD, Cai ZM, Wang Y, Wang L, Ge Z.   +8 more
europepmc   +1 more source