SQSTM1/p62 as a prognostic indicator in pancancer and nasopharyngeal carcinoma. [PDF]
Chen LL, Zhang ZY, Wu B, Lu MZ.
europepmc +1 more source
Liver injury in a preclinical model of short bowel syndrome is associated with impaired autophagy. [PDF]
Alligood DM +11 more
europepmc +1 more source
Gastrodin Injection Relieves Hypoxic-Ischemic Brain Injury in Newborn Rats by Regulating the P62/Nrf2/HO-1 Pathway. [PDF]
Wu S +7 more
europepmc +1 more source
Autophagy and ubiquitination in important swine viral infections: Host defense and viral antagonism. [PDF]
He Z, Liu M, Xie Q, Lu H, Guo C.
europepmc +1 more source
HMGB1 mediated autophagy and apoptosis in human nucleus pulposus cells; chloroquine amplified apoptosis by inhibiting autophagy. [PDF]
Khaleque MA +5 more
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Accumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer
Luo RZ +5 more
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Interaction Domains of p62: A Bridge Between p62 and Selective Autophagy
DNA and Cell Biology, 2013p62 is a multidomain protein that contains different kinds of protein-protein interaction domains, including an N-terminal PB1 domain, a ZZ-type zinc finger domain, a nuclear localization signal (NLS), an export motif (NES), the LC3-interacting region (LIR), the KEAP1-interacting region (KIR), and a C-terminal Ub-associated domain (UBA).
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Sequestosome 1/p62: across diseases
Biomarkers, 2012Sequestosome 1/p62 is a signal modulator or adaptor protein involved in receptor-mediated signal transduction. Sequestosome 1/p62 is gaining attention as it is involved in several diseases including Parkinson disease, Alzheimer disease, liver and breast cancer, Paget's disease of bone, obesity and insulin resistance.
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Presenilin-1 Regulates the Expression of p62 to Govern p62-dependent Tau Degradation
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