Results 171 to 180 of about 20,664 (187)

Oleuropein Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice by Targeting TGF-β1 Signaling Pathway. [PDF]

open access: yesBiomolecules
Zhang L   +10 more
europepmc   +1 more source

Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy via metabolic regulation. [PDF]

open access: yesJ Nanobiotechnology
Zhao X   +10 more
europepmc   +1 more source

The investigational anti-B7-H3 antibody-drug conjugate vobramitamab duocarmazine exerts anti-tumor activity in vitro and in vivo in pediatric sarcoma preclinical models. [PDF]

open access: yesCell Death Dis
Bianchi G   +11 more
europepmc   +1 more source

Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism. [PDF]

open access: yesElife
Li M   +15 more
europepmc   +1 more source

The pathogenesis of Noonan syndrome is modulated by NOC2L, a novel interactor of LZTR1 leading to impaired p53 signalling

open access: yes
Chatterjee S   +7 more
europepmc   +1 more source
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Signals of Oxidant-Induced Cardiomyocyte Hypertrophy: Key Activation of p70 S6 Kinase-1 and Phosphoinositide 3-Kinase

The Journal of Pharmacology and Experimental Therapeutics, 2002
Cardiomyocytes in culture can survive low or mild doses of oxidants but later increase cell volume and protein content. To understand the mechanism, we determined the early signaling events of oxidative stress. With 200 microM H2O2, the activity of p70 S6 kinase-1 (p70S6K1) increased at 30 min and reached a plateau at 90 min.
Victoria C, Tu   +2 more
openaire   +2 more sources

Angiopoietin-1 reduces iopromide-induced endothelial cell apoptosis through activation of phosphatidylinositol 3'-kinase/p70 S6 kinase.

International journal of tissue reactions, 2006
Radiocontrast media can induce vascular endothelial cell apoptosis. Apoptotic damage to the vascular endothelium is an important mechanism in vascular disease. Several growth factors with anti-apoptotic effects may help protect the vascular endothelium from apoptosis.
S O, Moon   +9 more
openaire   +2 more sources

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