Results 91 to 100 of about 1,463,960 (261)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
On ( p , q ) $(p,q)$ -analogue of two parametric Stancu-Beta operators
Journal of Inequalities and Applications, 2016 Our purpose is to introduce a two-parametric ( p , q ) $(p, q)$ -analogue of the Stancu-Beta operators. We study approximating properties of these operators using the Korovkin approximation theorem and also study a direct theorem.
Mohammad Mursaleen +2 more
doaj +1 more source
Erratum to: $$L(p, q)$$ L ( p , q ) -labeling and integer tension of a graph embedded on torus [PDF]
Journal of Combinatorial Optimization, 2014 Zhang, Xiaoling, Qian, Jianguo
openaire +2 more sources
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Some Properties of the (p,q)-Fibonacci and (p,q)-Lucas Polynomials
Journal of Applied Mathematics, 2012 Riordan arrays are useful for solving the combinatorial sums by the help of generating functions. Many theorems can be easily proved by Riordan arrays. In this paper we consider the Pascal matrix and define a new generalization of Fibonacci polynomials ...
GwangYeon Lee, Mustafa Asci
doaj +1 more source
APPROXIMATION BY MODIFIED LUPAS-STANCU OPERATORS BASED ON (p; q)-INTEGERS
Eurasian Mathematical Journal, 2021 Asif Khan +3 more
openaire +1 more source