Results 81 to 90 of about 1,481,183 (261)
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
A basic problem of ( p , q ) $(p,q)$ -Bernstein-type operators
Journal of Inequalities and Applications, 2017 In this note, we give an elaboration of a basic problem on convergence theorem of ( p , q ) $(p, q)$ -analogue of Bernstein-type operators. By some classical analysis techniques, we derive an exact class of ( p n , q n ) $(p_{n},q_{n})$ -integer ...
Qing-Bo Cai, Xiao-Wei Xu
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
On Lyapunov-type inequalities for ( p , q ) $(p,q)$ -Laplacian systems
Journal of Inequalities and Applications, 2017 We establish Lyapunov-type inequalities for a system involving one-dimensional ( p i , q i ) $(p_{i},q_{i})$ -Laplacian operators ( i = 1 , 2 $i=1,2$ ).
Mohamed Jleli, Bessem Samet
doaj +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Anderson-type inequality with applications in ( p , q ) $(p,q)$ -calculus
Journal of Inequalities and ApplicationsBased on the fundamental concepts of (p, q)-calculus, this paper introduces a key lemma that successfully generalizes the classical Anderson inequality to the (p, q)-calculus framework.
Jiao Yu
doaj +1 more source