Results 91 to 100 of about 1,822,255 (284)
Recent results on (p,q)-Laplacian type equations
, 2017 Start ing from a new sum decomposit ion of W1,p(RN ) ∩W1,q(RN ) and using a variat ional approach, we invest igate the existence of mult ipleweak solut ions of a (p, q)–Laplacian equat ion on RN , for 1 < q < p < N , with a sign–changing potent ial ...
Bartolo, Rossella
core
Q-Q plots of enriched alleles.
, 2018 Q-Q plots of Crohn’s disease association for AJ enriched A) protein-altering (protein-truncating and missense) and B) synonymous alleles in GWAS regions; and AJ enriched C) protein-altering and D) synonymous alleles outside of GWAS regions.
Richard H. Duerr (107855) +56 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Spherical Functions on SO0(p, q) / SO(p) × SO(q)
, 2014 . An integral formula is derived for the spherical functions on the symmetric space G/K = SO0(p, q) / SO(p) × SO(q). This formula allows us to state some results about the analytic continuation of the spherical functions to a tubular neighbourhood of ...
P. Sawyer
core
Q-Q plots for the distribution inferred by the models.
, 2018 A Diversity Q-Q plot for S3R-IBP. B Diversity Q-Q plot for the S-IBP. C Diversity Q-Q plot for the baseline model. D Ubiquity Q-Q plot for S3R-IBP. E Ubiquity Q-Q plot for S-IBP. F Ubiquity Q-Q plot for the baseline model.
Zoran Utkovski (3080073) +4 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Journal of Inequalities and Applications, 2019 In this paper, some qualitative approximation results for the (p,q) $(p,q)$-Bernstein operators Bp,qn(f;x) $B_{p,q}^{n}(f;x)$ are obtained for the Cauchy kernel 1x−α $\frac{1}{x-\alpha }$ with a pole α∈[0,1] $\alpha \in {}[ 0,1]$ for q>p>1 $q>p>1$.
Faisal Khan +3 more
doaj +1 more source
The second Hyper-Zagreb index of VC5C7 [p, q] and HC5C7 [p, q] nanotubes
The first and second Hyper-Zagreb indices are the molecular descriptors that describe the structures of chemical compounds and they help us to predict certain physicochemical properties. In this paper, we studied the first and second Hyper-Zagreb indices
ZEREN, Yusuf +2 more
core +1 more source