Results 71 to 80 of about 24,653,664 (251)
The metabolic cost of balance in cycling
, 2013 Ergometers and stationary bicycle trainers are commonly used in laboratories to simulate overground riding. Missing from such instrumentation, however, is any demand for balance and the fraction of the metabolic cost associated with dynamic balance.
Smith, Gerald A +3 more
core +1 more source
Patients’ perspectives on the implementation of intra-dialytic cycling—a phenomenographic study
Implementation Science, 2012 Background Adults undergoing haemodialysis have significantly reduced physical capacity and run a high risk of developing cardiovascular complications.
Heiwe Susanne, Tollin Helena
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Routledge Companion to Cycling Studies [PDF]
, 2021 This is an Accepted Manuscript of a book chapter published by Routledge in Routledge Companion to Cycling Studies on 14/12/2022, available online: https://www.routledge.com/Routledge-Companion-to-Cycling/Norcliffe-Brogan-Cox-Gao-Hadland-Hanlon-Jones-Oddy-
Cox, Peter
core +1 more source
Neighbourhood safety and leisure-time physical activity among Dutch adults: a multilevel perspective
International Journal of Behavioral Nutrition and Physical Activity, 2013 Background Several neighbourhood elements have been found to be related to leisure-time walking and cycling. However, the association with neighbourhood safety remains unclear. This study aimed to assess the association of neighbourhood-level safety with
Kramer Daniëlle +3 more
doaj +1 more source
Spectral properties of muscle activation during incremental cycling test [PDF]
, 2015 It is uncertain whether fatigue and workload would affect muscle recruitment during cycling. To infer on changes in priority for recruitment of motor units, we assessed the combined effects of fatigue and workload during an incremental cycling test to ...
Diefenthaeler, Fernando +3 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Effect of fluoride application during radiotherapy on enamel demineralization
Journal of Applied Oral Science, 2018 Radiation-related caries are one the most undesired reactions manifested during or after head and neck radiotherapy. Fluoride application is an important strategy to reduce demineralization and enhance remineralizaton.
Camila de Carvalho Almança Lopes +5 more
doaj +1 more source