Results 121 to 130 of about 25,979 (261)

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

P. gingivalis-host interactions direct antibiotic adjuvants for periodontitis antimicrobial therapy. [PDF]

Int J Oral Sci
Liu X, Yuan Z, Wan Z, Yuan X, Wang Y, Gao Y, Zhang L, Song R, Sang J, Wang Y, Han Y, Zhao Y, Wang CY.   +12 more
europepmc   +1 more source

Prediction of Druggable Allosteric Sites of Undruggable Multidrug Resistance Efflux Pump P. Gingivalis Proteins. [PDF]

Biomed Eng Comput Biol, 2023
Yadalam PK, Anegundi RV, Heboyan A.
europepmc   +1 more source

Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold, Chia Wei Cheah, Rathna Devi Vaithilingam   +2 more
wiley   +1 more source

Pathogenicity of <i>P. gingivalis</i> strains carrying clusters of specific polymorphic variants of peptidylarginine deiminase gene. [PDF]

Front Cell Infect Microbiol
Strzelec K, Dziedzic-Kowalska A, Ferenc K, Łazarz-Bartyzel K, Olszewska-Czyż I, Rąpalska I, Sieroń Ł, Aptekorz M, Romanik M, Mendrek B, Oleszko-Torbus N, Kowalczuk A, Kusz D, Kaczmarzyk T, Cześnikiewicz-Guzik M, Niemiec P, Wasik TJ, Gawron K.   +17 more
europepmc   +1 more source

Stevioside reduces inflammation in periodontitis by changing the oral bacterial composition and inhibiting P. gingivalis in mice. [PDF]

BMC Oral Health, 2023
Han W, Jiao Y, Mi S, Han S, Xu J, Li S, Liu Y, Guo L.   +7 more
europepmc   +1 more source

Periodontal Diseases as a Public Health Challenge: Rationale, Prevention, Equity, and Sustainable Care—A Global Call for Action

Journal of Periodontal Research, EarlyView.
Periodontal diseases affect over a billion people worldwide, yet remain weakly integrated into global non‐communicable disease agendas. We propose reorienting periodontal care around three public health opportunities—upstream prevention, diagnosis fit for both clinical and population use, and value‐based treatment—prioritizing prevention, value, and ...
Marco A. Peres, Lijian Jin, Gustavo G. Nascimento, Philip M. Preshaw, Eero Juhani Raittio, Dian Yi Chow, John Rong Hao Tay   +6 more
wiley   +1 more source

Epithelial Inflammatory iNOS-Nitrate Axis Enhances <i>P. gingivalis</i> Pathogenicity via <i>V. parvula</i> in Diabetes-Associated Periodontitis. [PDF]

Int J Mol Sci
Wei L, Liu H, Shen Z, Song Z, Huang S, Lin Z, Huang X.   +6 more
europepmc   +1 more source

Metronidazole Potentiation by Panax Ginseng and Symphytum officinale: A New Strategy for P. gingivalis Infection Control. [PDF]

Antibiotics (Basel), 2023
Ibrahim SM, Al-Mizraqchi AS, Haider J.
europepmc   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source