Results 51 to 60 of about 6,447,121 (289)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
The frequent insignificance of a “significant” p-value
, 2021 Null hypothesis significance testing (NHST) and p-values are widespread in the cardiac surgical literature but are frequently misunderstood and misused. The purpose of the review is to discuss major disadvantages of p-values and suggest alternatives.
Geoffrey Cumming (9483971) +2 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Efficient Computation of the Shapley Value for Centrality in Networks
, 2010 The Shapley Value is arguably the most important normative solution concept in coalitional games. One of its applications is in the domain of networks, where the Shapley Value is used to measure the relative importance of individual nodes.
Michalak, Tomasz P +10 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source
Indian Journal of Community MedicineMedical research plays a crucial role in advancing our understanding of various aspects related to health, including disease, risk factors, and patient management.
Yousif AbdulRaheem
doaj +1 more source
JNCI Cancer Spectrum, 2020 AbstractRecently, a controversy has erupted regarding the use of statistical significance tests and the associated P values. Prominent academic statisticians have recommended that the use of statistical tests be discouraged or not used at all. This has naturally led to a lot of confusion among research investigators about the support in the academic ...
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
Jurnal Ilmu Kesehatan Masyarakat, 2020 Tailor isone ofthe professions that has MSDsrisk. It isbecause of theworking posture, such as sitting for a long time and repetitive movements. The purpose of thisstudy is to determinerelationshipbetweenworking postures and Musculoskeletal Disordes ...
Betty Andriani, +2 more
doaj +1 more source