Results 1 to 10 of about 38,555 (108)

The Fragility Index of Randomized Controlled Trials for Preterm Neonates [PDF]

Frontiers in Pediatrics, 2022
BackgroundAs a metric to determine the robustness of trial results, the fragility index (FI) is the number indicating how many patients would be required to reverse the significant results.
Huiyi Li, Zhenyu Liang, Qiong Meng, Xin Huang, Xin Huang   +4 more
doaj   +2 more sources

Fragility index of positive phase II and III randomised clinical trials of treatments for hepatocellular carcinoma (2002–2022) [PDF]

JHEP Reports, 2023
Background & Aims: The fragility index (FI), i.e., theminimum number of best survivors reassigned to the control group required to revert the statistically significant result of a clinical trial to non-significant, is a metric to evaluate the ...
Sabrina Sidali, Nanthara Sritharan, Claudia Campani, Jules Gregory, François Durand, Nathalie Ganne-Carrié, Maxime Ronot, Vincent Lévy, Jean-Charles Nault   +8 more
doaj   +2 more sources

Recurring low statistical robustness in orthopaedic surgery: A systematic review of 84 fragility index studies [PDF]

Journal of Experimental Orthopaedics
Purpose Increasing attention has been directed towards the fragility index (FI) and reverse fragility index (RFI) in orthopaedic surgery. The purpose of this study was to amalgamate the FI and RFI literature in orthopaedic surgery, and critically ...
Hassaan Abdel Khalik, Helena Son, Krishnateja Narayana, Moin Khan, Olufemi Rolland Ayeni   +4 more
doaj   +2 more sources

Assessing the fragility index of randomized controlled trials supporting perioperative care guidelines: A methodological survey protocol. [PDF]

PLoS ONE
IntroductionThe Fragility Index (FI) and the FI family are statistical tools that measure the robustness of randomized controlled trials (RCT) by examining how many patients would need a different outcome to change the statistical significance of the ...
Margarita Otalora-Esteban, Martha Beatriz Delgado-Ramirez, Fabian Gil, Lehana Thabane   +3 more
doaj   +2 more sources

Fragility Index and Fragility Quotient in Statistically Significant Randomized Controlled Trials in Plastic Breast Surgery [PDF]

Plastic and Reconstructive Surgery, Global Open
Background:. The fragility index (FI) was conceived as an adjunct to the P value, signifying the strength of statistically significant results. The index states the minimal number of patients whose outcome must be changed from “event” to “nonevent” for ...
Ron Skorochod, MD, MPH, Yoav Gronovich, MD, MBA   +1 more
doaj   +2 more sources

Triglyceride Glucose Index is Strongly Associated with a Fragility Fracture in Postmenopausal Elderly Females with Type 2 Diabetes Mellitus Combined with Osteoporosis: A 6-Year Follow-Up Study

Clinical Interventions in Aging, 2023
Jiangmei Pan,1,2,* Xiuxian Huang,1,* Qiu Wang,1,* Jingxia Sun,1,* Zhenwei Zhai,1,* Jiacheng Mo,3 Jianhao Huang,1 Wensheng Lu1 1Department of Endocrinology and Metabolism, Guangxi Academy of Medical Sciences and the People’s Hospital ...
Pan J, Huang X, Wang Q, Sun J, Zhai Z, Mo J, Huang J, Lu W   +7 more
doaj   +2 more sources

Assessing the Robustness of Results From Clinical Trials and Meta-Analyses With the Fragility Index [PDF]

American Journal of Obstetrics and Gynecology, 2023
Luis Sanchez-Ramos, Lifeng Lin, Martin Wells   +2 more
exaly   +2 more sources

Paediatric Surgical Trials, Their Fragility Index, and Why to Avoid Using It to Evaluate Results [PDF]

Pediatric Surgery International, 2022
Christina Oetzmann von Sochaczewski, Arne Schröder, Oliver J Muensterer   +2 more
exaly   +2 more sources

Empirical Assessment of Fragility Index Based on a Large Database of Clinical Studies in the Cochrane Library [PDF]

Journal of Evaluation in Clinical Practice, 2023
Lifeng Lin, Aiwen Xing
exaly   +2 more sources

The Fragility Index Can Be Used for Sample Size Calculations in Clinical Trials [PDF]

Journal of Clinical Epidemiology, 2021
Mary Charlson, Mario Gaudino, Martin Wells   +2 more
exaly   +2 more sources