Results 21 to 30 of about 8,391,091 (301)

Recurring low statistical robustness in orthopaedic surgery: A systematic review of 84 fragility index studies [PDF]

Journal of Experimental Orthopaedics
Purpose Increasing attention has been directed towards the fragility index (FI) and reverse fragility index (RFI) in orthopaedic surgery. The purpose of this study was to amalgamate the FI and RFI literature in orthopaedic surgery, and critically ...
Hassaan Abdel Khalik, Helena Son, Krishnateja Narayana, Moin Khan, Olufemi Rolland Ayeni   +4 more
doaj   +2 more sources

Factors that impact fragility index and their visualizations. [PDF]

J Eval Clin Pract, 2021
AbstractRationale aims and objectivesAs the recent literature has growing concerns about research replicability and the misuse and misconception of P‐values, the fragility index (FI) has been an attractive measure to assess the robustness (or fragility) of clinical study results with binary outcomes.
Lin L.
europepmc   +3 more sources

Fragility Index of Recently Published Meta-Analyses in Pediatric Urology: A Striking Observation. [PDF]

Cureus, 2021
Background and objective Fragility Index (FI) of meta-analyses determines their stability in terms of the level of confidence and strength behind the results depicted by them.
Anand S, Kainth D.
europepmc   +2 more sources

Evaluating the properties of the fragility index of meta-analyses. [PDF]

BMC Med Res Methodol
Abstract Background The fragility index (FI) has become an increasingly popular supplementary measure for evaluating the robustness of a study’s conclusions. While initially developed for individual clinical trials, the FI has been extended to meta-analyses (MAs) of multiple studies.
Xing A, Xing X, Murad MH, Lin L.
europepmc   +4 more sources

Fragility Index and Fragility Quotient in Statistically Significant Randomized Controlled Trials in Plastic Breast Surgery [PDF]

Plastic and Reconstructive Surgery, Global Open
Background:. The fragility index (FI) was conceived as an adjunct to the P value, signifying the strength of statistically significant results. The index states the minimal number of patients whose outcome must be changed from “event” to “nonevent” for ...
Ron Skorochod, MD, MPH, Yoav Gronovich, MD, MBA   +1 more
doaj   +2 more sources

Review of Fragility Index

, 2022
This project provides data and code files for the manuscript "Assessing the robustness of results from clinical trials and meta-analyses with the fragility index" by Lifeng Lin, Aiwen Xing, Haitao Chu, M. Hassan Murad, Chang Xu, Benjamin R.
Aiwen Xing, Lifeng Lin
core   +9 more sources

The Fragility Index for Assessing the Robustness of the Statistically Significant Results of Experimental Clinical Studies. [PDF]

J Gen Intern Med, 2022
Ho AK.
europepmc   +2 more sources

Significance of fragility index in meta-analysis. [PDF]

Saudi J Anaesth
Borkar NB, Nair A.
europepmc   +3 more sources

The Fragility Index in randomised clinical trials supporting clinical practice guidelines for acute coronary syndrome: measuring robustness from a different perspective.

European heart journal. Acute cardiovascular care, 2023
BACKGROUND In randomised clinical trials (RCTs) rejecting the null hypothesis, the fragility index (FI) yields the minimum number of participants who would need to have had a different outcome for the results of the trial to become non-significant.
Maribel González-del-Hoyo, Caterina Mas-Lladó, Laura Blaya-Peña, Joan Siquier-Padilla, V. Peral, X. Rosselló   +5 more
semanticscholar   +1 more source

Comments on "How Fragile Are the Results of a Trial? The Fragility Index" by Dettori and Norvell. [PDF]

Global Spine J, 2020
Evaniew N.
europepmc   +4 more sources